Research workbench
AlphaFold monomer V2.0 prediction for retinoid isomerohydrolase (Q28175)
Analyse AlphaFold monomer V2.0 prediction for retinoid isomerohydrolase (Q28175) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q28175
- Type
- protein
- Length
- 533 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x6f21693d56aA6FE47fEAebd994D4DF52A0B25787
- Molecule
- Retinoid isomerohydrolase
- UniProt
- Q28175
- Pockets
- 5 · best druggability 0.85
Structure
1 distinct chain · 12% helix, 43% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Retinoid isomerohydrolase | protein | 533 | 12% helix, 43% strand | Q28175 |
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 520 | 0.85 | 0.90 | 65 | empty |
| 2 | 506 | 0.78 | 0.86 | 47 | empty |
| 3 | 228 | 0.62 | 0.81 | 27 | empty |
| 4 | 55 | 0.39 | 0.81 | 13 | empty |
| 5 | 76 | 0.36 | 0.76 | 23 | empty |
Compared structures
- 4F30 · Structure of RPE65: P6522 crystal form grown in ammonium phosphate solution · an experimental structure of the same protein · chain A against A, TM-score 0.97
- 4F30 · Structure of RPE65: P6522 crystal form grown in ammonium phosphate solution · an experimental structure of the same protein · chain A against A, TM-score 0.97
- 4F3A · Structure of RPE65: P6522 crystal form, iridium derivative · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 4F3A · Structure of RPE65: P6522 crystal form, iridium derivative · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 3FSN · Crystal structure of RPE65 at 2.14 angstrom resolution · an experimental structure of the same protein · chain A against B, TM-score 0.96
- 3FSN · Crystal structure of RPE65 at 2.14 ångström resolution · an experimental structure of the same protein · chain A against B, TM-score 0.96
- 4F3D · Structure of RPE65: P65 crystal form grown in Fos-Choline-10 · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 4F3D · Structure of RPE65: P65 crystal form grown in fos-choline-10 · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 4F2Z · Crystal structure of RPE65 in a lipid environment · an experimental structure of the same protein · chain A against A, TM-score 0.96
- 4F2Z · Crystal structure of RPE65 in a lipid environment · an experimental structure of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q28175
- Elsewhere: UniProt Q28175 · AlphaFold DB Q28175
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