Research workbench
AlphaFold monomer V2.0 prediction for replication factor C subunit 5 (P40937)
Analyse AlphaFold monomer V2.0 prediction for replication factor C subunit 5 (P40937) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P40937
- Type
- protein
- Length
- 340 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7a1388B6Aad67B04634A32f63b8A6D6005eab86c
- Molecule
- Replication factor C subunit 5
- UniProt
- P40937
- Pockets
- 1 · best druggability 0.73
Structure
1 distinct chain · 61% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Replication factor C subunit 5 | protein | 340 | 61% helix, 9% strand | P40937 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 182 | 0.73 | 0.90 | 30 | empty |
Compared structures
- 8UMU · Atomic model of the human CTF18-RFC-PCNA binary complex in the four-subunit binding state… · an experimental structure of the same protein · chain A against C, TM-score 0.91
- 8UII · Cryo-EM map of human clamp-clamp loader ATAD5-RFC-closed PCNA complex in intermediate… · an experimental structure of the same protein · chain A against C, TM-score 0.90
- 8UMT · Atomic model of the human CTF18-RFC-PCNA binary complex in the three-subunit binding… · an experimental structure of the same protein · chain A against C, TM-score 0.90
- 8UNJ · Atomic model of the human CTF18-RFC alone in the apo state (State 1) · an experimental structure of the same protein · chain A against C, TM-score 0.88
- 6VVO · Structure of the human clamp loader (Replication Factor C, RFC) bound to the sliding… · an experimental structure of the same protein · chain A against C, TM-score 0.88
- 6VVO · Structure of the human clamp loader (replication factor C, rfc) bound to the sliding… · an experimental structure of the same protein · chain A against C, TM-score 0.88
- 8UI7 · Cryo-EM map of human clmap-clamp loader ATAD5-RFC-gapped PCNA complex in intermediate… · an experimental structure of the same protein · chain A against C, TM-score 0.87
- 8UI9 · Cryo-EM map of human clamp-clamp loader ATAD5-RFC-cracked PCNA complex in intermediate… · an experimental structure of the same protein · chain A against C, TM-score 0.87
- 8UMY · Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex with narrow PCNA opening… · an experimental structure of the same protein · chain A against C, TM-score 0.87
- 8UMV · Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex with narrow PCNA opening… · an experimental structure of the same protein · chain A against C, TM-score 0.87
- 8UMW · Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex in the five-subunit binding… · an experimental structure of the same protein · chain A against C, TM-score 0.87
- 8UI8 · Cryo-EM map of human clamp-clamp loader ATAD5-RFC-two PCNAs complex in intermediate state… · an experimental structure of the same protein · chain A against C, TM-score 0.87
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P40937
- Elsewhere: UniProt P40937 · AlphaFold DB P40937
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