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AlphaFold monomer V2.0 prediction for replication factor C subunit 5 (P40937)

Analyse AlphaFold monomer V2.0 prediction for replication factor C subunit 5 (P40937) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P40937
Type
protein
Length
340 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x7a1388B6Aad67B04634A32f63b8A6D6005eab86c
Molecule
Replication factor C subunit 5
UniProt
P40937
Pockets
1 · best druggability 0.73

Structure

1 distinct chain · 61% helix, 9% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AReplication factor C subunit 5protein34061% helix, 9% strandP40937

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11820.730.9030empty

Compared structures

  • 8UMU · Atomic model of the human CTF18-RFC-PCNA binary complex in the four-subunit binding state… · an experimental structure of the same protein · chain A against C, TM-score 0.91
  • 8UII · Cryo-EM map of human clamp-clamp loader ATAD5-RFC-closed PCNA complex in intermediate… · an experimental structure of the same protein · chain A against C, TM-score 0.90
  • 8UMT · Atomic model of the human CTF18-RFC-PCNA binary complex in the three-subunit binding… · an experimental structure of the same protein · chain A against C, TM-score 0.90
  • 8UNJ · Atomic model of the human CTF18-RFC alone in the apo state (State 1) · an experimental structure of the same protein · chain A against C, TM-score 0.88
  • 6VVO · Structure of the human clamp loader (Replication Factor C, RFC) bound to the sliding… · an experimental structure of the same protein · chain A against C, TM-score 0.88
  • 6VVO · Structure of the human clamp loader (replication factor C, rfc) bound to the sliding… · an experimental structure of the same protein · chain A against C, TM-score 0.88
  • 8UI7 · Cryo-EM map of human clmap-clamp loader ATAD5-RFC-gapped PCNA complex in intermediate… · an experimental structure of the same protein · chain A against C, TM-score 0.87
  • 8UI9 · Cryo-EM map of human clamp-clamp loader ATAD5-RFC-cracked PCNA complex in intermediate… · an experimental structure of the same protein · chain A against C, TM-score 0.87
  • 8UMY · Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex with narrow PCNA opening… · an experimental structure of the same protein · chain A against C, TM-score 0.87
  • 8UMV · Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex with narrow PCNA opening… · an experimental structure of the same protein · chain A against C, TM-score 0.87
  • 8UMW · Atomic model of the human CTF18-RFC-PCNA-DNA ternary complex in the five-subunit binding… · an experimental structure of the same protein · chain A against C, TM-score 0.87
  • 8UI8 · Cryo-EM map of human clamp-clamp loader ATAD5-RFC-two PCNAs complex in intermediate state… · an experimental structure of the same protein · chain A against C, TM-score 0.87

Analyse

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