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UniProt P40937

Replication factor C subunit 5 (P40937)

Replication factor C subunit 5 (UniProt P40937): 5 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 27 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
P40937
Protein
Replication factor C subunit 5
Experimental structures
5
Predicted models
1
Ligands
2
Pockets
27 · 4 records with a druggable one

Structures

6 records of P40937 in the MolNFT archive: 5 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6VVOStructure of the human clamp loader (replication factor C, rfc) bound to the sliding clamp…electron microscopyCMG, AGS—
7Z6HStructure of DNA-bound human RAD17-RFC clamp loader and 9-1-1 checkpoint clampelectron microscopyGAGS9 (best 0.81)
7Z6HStructure of DNA-bound human RAD17-rfc clamp loader and 9-1-1 checkpoint clampelectron microscopyGAGS—
8UI7Cryo-EM map of human clmap-clamp loader ATAD5-RFC-gapped PCNA complex in intermediate state 3electron microscopyCMG, AGS7 (best 0.88)
8UMYAtomic model of the human CTF18-RFC-PCNA-DNA ternary complex with narrow PCNA opening state II…electron microscopyCMG, AGS10 (best 0.80)
P40937AlphaFold monomer V2.0 prediction for replication factor C subunit 5 (P40937)predictedA—1 (best 0.73)

Ligands

  • AGS · Phosphothiophosphoric acid-adenylate ester · in 5 records
  • MG · Magnesium ion · in 3 records

Experiment against prediction

Elsewhere

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