Research workbench
AlphaFold monomer V2.0 prediction for V(D)J recombination-activating protein 1 (P15919)
Analyse AlphaFold monomer V2.0 prediction for V(D)J recombination-activating protein 1… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P15919
- Type
- protein
- Length
- 1,040 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xbff27Dc0a932A6E0d9Fe883AAbD1BF27bB95A69F
- Molecule
- V(D)J recombination-activating protein 1
- UniProt
- P15919
- Pockets
- 6 · best druggability 0.70
Structure
1 distinct chain · 40% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | V(D)J recombination-activating protein 1 | protein | 1040 | 40% helix, 10% strand | P15919 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 64 | 0.70 | 0.96 | 23 | empty |
| 2 | 460 | 0.67 | 0.78 | 32 | empty |
| 3 | 316 | 0.57 | 0.76 | 34 | empty |
| 4 | 253 | 0.54 | 0.77 | 29 | empty |
| 5 | 73 | 0.35 | 0.76 | 12 | empty |
Compared structures
- 5ZE2 · Hairpin complex, RAG1/2-hairpin 12RSS/23RSS complex in 5MM MN2+ for 2 min at 4'C · an experimental structure of the same protein · chain A against C, TM-score 0.60
- 5ZE2 · Hairpin Complex, RAG1/2-hairpin 12RSS/23RSS complex in 5mM Mn2+ for 2 min at 4'C · an experimental structure of the same protein · chain A against C, TM-score 0.60
- 5ZE1 · Hairpin forming complex, RAG1/2-nicked 12RSS/23RSS complex in 2MM MN2+ for 10 min at 4'C · an experimental structure of the same protein · chain A against C, TM-score 0.60
- 5ZE1 · Hairpin Forming Complex, RAG1/2-Nicked 12RSS/23RSS complex in 2mM Mn2+ for 10 min at 4'C · an experimental structure of the same protein · chain A against C, TM-score 0.60
- 5ZDZ · Hairpin forming complex, RAG1/2-nicked 12RSS/23RSS complex in CA2+ · an experimental structure of the same protein · chain A against C, TM-score 0.60
- 5ZDZ · Hairpin Forming Complex, RAG1/2-Nicked 12RSS/23RSS complex in Ca2+ · an experimental structure of the same protein · chain A against C, TM-score 0.60
- 5ZE0 · Hairpin Forming Complex, RAG1/2-Nicked(with Dideoxy) 12RSS/23RSS complex in Mg2+ · an experimental structure of the same protein · chain A against C, TM-score 0.60
- 5ZE0 · Hairpin forming complex, RAG1/2-NICKED(WITH dideoxy) 12RSS/23RSS complex in MG2+ · an experimental structure of the same protein · chain A against C, TM-score 0.60
- 6OET · Cryo-EM structure of mouse RAG1/2 STC complex · an experimental structure of the same protein · chain A against C, TM-score 0.59
- 6OET · Cryo-EM structure of mouse RAG1/2 stc complex · an experimental structure of the same protein · chain A against C, TM-score 0.59
- 6CIJ · Cryo-EM structure of mouse RAG1/2 hfc complex containing partial HMGB1 LINKER(3.9 a) · an experimental structure of the same protein · chain A against C, TM-score 0.59
- 6CIJ · Cryo-EM structure of mouse RAG1/2 HFC complex containing partial HMGB1 linker(3.9 A) · an experimental structure of the same protein · chain A against C, TM-score 0.59
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P15919
- Elsewhere: UniProt P15919 · AlphaFold DB P15919
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