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AlphaFold monomer V2.0 prediction for orotate phosphoribosyltransferase (P0A7E3)

Analyse AlphaFold monomer V2.0 prediction for orotate phosphoribosyltransferase (P0A7E3) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P0A7E3
Type
protein
Length
213 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x5BeA89782341f98147F2D811B063F91F0aE7D7bF
Molecule
Orotate phosphoribosyltransferase
UniProt
P0A7E3
Pockets
1 · best druggability 0.59

Structure

1 distinct chain · 45% helix, 26% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AOrotate phosphoribosyltransferaseprotein21345% helix, 26% strandP0A7E3

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12730.590.7932empty

Compared structures

  • 1ORO · A flexible loop at the dimer interface is a part of the active site of the adjacent… · an experimental structure of the same protein · chain A against A, TM-score 0.98
  • 1ORO · A flexible loop at the dimer interface is a part of the active site of the adjacent… · an experimental structure of the same protein · chain A against A, TM-score 0.98
  • 6TAK · Crystal structure of Escherichia coli Orotate Phosphoribosyltransferase in complex with… · an experimental structure of the same protein · chain A against BBB, TM-score 0.98
  • 6TAI · Crystal structure of Escherichia coli Orotate Phosphoribosyltransferase with an empty… · an experimental structure of the same protein · chain A against AAA, TM-score 0.94
  • 6TAJ · Crystal structure of Escherichia coli Orotate Phosphoribosyltransferase in complex with… · an experimental structure of the same protein · chain A against AAA, TM-score 0.94

Analyse

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