AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor PRP46 (Q12417)

Structure

1 distinct chain · 17% helix, 37% strand (DSSP).

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Compared structures

• 9DTR · Structure of the yeast post-catalytic P complex spliceosome at 2.3 Angstrom resolution · an experimental structure of the same protein · chain A against J, TM-score 0.76
• 6J6H · Cryo-EM structure of the yeast B*-a1 complex at an average resolution of 3.6 angstrom · an experimental structure of the same protein · chain A against O, TM-score 0.75
• 6J6H · Cryo-EM structure of the yeast B*-A1 complex at an average resolution of 3.6 ångström · an experimental structure of the same protein · chain A against O, TM-score 0.75
• 6J6Q · Cryo-EM structure of the yeast B*-B2 complex at an average resolution of 3.7 ångström · an experimental structure of the same protein · chain A against O, TM-score 0.75
• 6J6Q · Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom · an experimental structure of the same protein · chain A against O, TM-score 0.75
• 6J6G · Cryo-EM structure of the yeast B*-A2 complex at an average resolution of 3.2 ångström · an experimental structure of the same protein · chain A against O, TM-score 0.75
• 6J6G · Cryo-EM structure of the yeast B*-a2 complex at an average resolution of 3.2 angstrom · an experimental structure of the same protein · chain A against O, TM-score 0.75
• 6J6N · Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom · an experimental structure of the same protein · chain A against O, TM-score 0.75
• 6J6N · Cryo-EM structure of the yeast B*-B1 complex at an average resolution of 3.86 ångström · an experimental structure of the same protein · chain A against O, TM-score 0.75
• 6BK8 · S. cerevisiae spliceosomal post-catalytic P complex · an experimental structure of the same protein · chain A against D, TM-score 0.75
• 6BK8 · S. cerevisiae spliceosomal post-catalytic P complex · an experimental structure of the same protein · chain A against D, TM-score 0.75
• 6EXN · Post-catalytic P complex spliceosome with 3' splice site docked · an experimental structure of the same protein · chain A against J, TM-score 0.74

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q12417
• Elsewhere: UniProt Q12417 · AlphaFold DB Q12417