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AlphaFold monomer V2.0 prediction for pre-mRNA-processing protein 45 (P28004)

Analyse AlphaFold monomer V2.0 prediction for pre-mRNA-processing protein 45 (P28004) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P28004
Type
protein
Length
379 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xBeB220F0B5b0C48F46B5DDd3E3b071BC0827f8D6
Molecule
Pre-mRNA-processing protein 45
UniProt
P28004
Pockets
1 · best druggability 0.33

Structure

1 distinct chain · 35% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APre-mRNA-processing protein 45protein37935% helix, 0% strandP28004

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1680.330.7514empty

Compared structures

  • 6J6N · Cryo-EM structure of the yeast B*-B1 complex at an average resolution of 3.86 ångström · an experimental structure of the same protein · chain A against P, TM-score 0.38
  • 6J6N · Cryo-EM structure of the yeast B*-b1 complex at an average resolution of 3.86 angstrom · an experimental structure of the same protein · chain A against P, TM-score 0.38
  • 6J6H · Cryo-EM structure of the yeast B*-a1 complex at an average resolution of 3.6 angstrom · an experimental structure of the same protein · chain A against P, TM-score 0.38
  • 6J6H · Cryo-EM structure of the yeast B*-A1 complex at an average resolution of 3.6 ångström · an experimental structure of the same protein · chain A against P, TM-score 0.38
  • 5GMK · Cryo-EM structure of the Catalytic Step I spliceosome (C complex) at 3.4 angstrom… · an experimental structure of the same protein · chain A against P, TM-score 0.38
  • 5GMK · Cryo-EM structure of the catalytic step I spliceosome (C complex) at 3.4 ångström… · an experimental structure of the same protein · chain A against P, TM-score 0.38
  • 6J6Q · Cryo-EM structure of the yeast B*-B2 complex at an average resolution of 3.7 ångström · an experimental structure of the same protein · chain A against P, TM-score 0.38
  • 6J6Q · Cryo-EM structure of the yeast B*-b2 complex at an average resolution of 3.7 angstrom · an experimental structure of the same protein · chain A against P, TM-score 0.38
  • 5YLZ · Cryo-EM structure of the post-catalytic spliceosome from saccharomyces cerevisiae at 3.6… · an experimental structure of the same protein · chain A against Q, TM-score 0.38
  • 5YLZ · Cryo-EM Structure of the Post-catalytic Spliceosome from Saccharomyces cerevisiae at 3.6… · an experimental structure of the same protein · chain A against Q, TM-score 0.38
  • 6J6G · Cryo-EM structure of the yeast B*-A2 complex at an average resolution of 3.2 ångström · an experimental structure of the same protein · chain A against P, TM-score 0.38
  • 6J6G · Cryo-EM structure of the yeast B*-a2 complex at an average resolution of 3.2 angstrom · an experimental structure of the same protein · chain A against P, TM-score 0.38

Analyse

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