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AlphaFold monomer V2.0 prediction for pyridoxine-5'-phosphate oxidase (Q9NVS9)

Analyse AlphaFold monomer V2.0 prediction for pyridoxine-5'-phosphate oxidase (Q9NVS9) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9NVS9
Type
protein
Length
261 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xcF79EabFD85CBBEc9F4c34c0156e5B2407B7C5fd
Molecule
Pyridoxine-5'-phosphate oxidase
UniProt
Q9NVS9
Pockets
2 · best druggability 0.37

Structure

1 distinct chain · 25% helix, 27% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APyridoxine-5'-phosphate oxidaseprotein26125% helix, 27% strandQ9NVS9

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1970.370.7515empty
2530.270.7313empty

Compared structures

  • 1NRG · Structure and properties of recombinant human pyridoxine-5'-phosphate oxidase · an experimental structure of the same protein · chain A against A, TM-score 0.80
  • 1NRG · Structure and Properties of Recombinant Human Pyridoxine-5'-Phosphate Oxidase · an experimental structure of the same protein · chain A against A, TM-score 0.80
  • 8QYT · Human Pyridoxine-5'-phosphate oxidase in complex with PLP · an experimental structure of the same protein · chain A against A, TM-score 0.80
  • 8QYW · Human Pyridoxine-5'-phosphate oxidase mutant R225H · an experimental structure of the same protein · chain A against A, TM-score 0.79
  • 3HY8 · Crystal structure of human pyridoxine 5'-phosphate oxidase R229W mutant · an experimental structure of the same protein · chain A against A, TM-score 0.79
  • 3HY8 · Crystal Structure of Human Pyridoxine 5'-Phosphate Oxidase R229W Mutant · an experimental structure of the same protein · chain A against A, TM-score 0.79
  • 6H00 · Crystal structure of human pyridoxine 5-phophate oxidase, R116Q variant · an experimental structure of the same protein · chain A against A, TM-score 0.77
  • 6H00 · Crystal structure of human pyridoxine 5-phophate oxidase, R116Q variant · an experimental structure of the same protein · chain A against A, TM-score 0.77

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