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AlphaFold monomer V2.0 prediction for purine nucleoside phosphorylase (P55859)

Analyse AlphaFold monomer V2.0 prediction for purine nucleoside phosphorylase (P55859) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P55859
Type
protein
Length
289 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xa73BAb1DabE4333A884D03393eAa10c3B4215494
Molecule
Purine nucleoside phosphorylase
UniProt
P55859
Pockets
2 · best druggability 0.67

Structure

1 distinct chain · 34% helix, 23% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APurine nucleoside phosphorylaseprotein28934% helix, 23% strandP55859

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11500.670.8825empty
2940.450.8021empty

Compared structures

  • 1A9P · Bovine purine nucleoside phosphorylase complexed with 9-deazainosine and phosphate · an experimental structure of the same protein · chain A against A, TM-score 0.98
  • 1A9P · Bovine purine nucleoside phosphorylase complexed with 9-deazainosine and phosphate · an experimental structure of the same protein · chain A against A, TM-score 0.98
  • 1A9T · Bovine purine nucleoside phosphorylase complexed with 9-deazainosine and phosphate · an experimental structure of the same protein · chain A against A, TM-score 0.97
  • 1A9T · Bovine purine nucleoside phosphorylase complexed with 9-deazainosine and phosphate · an experimental structure of the same protein · chain A against A, TM-score 0.97
  • 4PNP · The high resolution crystal structure of bovine spleen purine nucleoside phosphorylase in… · an experimental structure of the same protein · chain A against A, TM-score 0.97
  • 4PNP · The high resolution crystal structure of bovine spleen purine nucleoside phosphorylase in… · an experimental structure of the same protein · chain A against A, TM-score 0.97
  • 1A9S · Bovine purine nucleoside phosphorylase complexed with inosine and sulfate · an experimental structure of the same protein · chain A against A, TM-score 0.97
  • 1A9S · Bovine purine nucleoside phosphorylase complexed with inosine and sulfate · an experimental structure of the same protein · chain A against A, TM-score 0.97
  • 1A9O · Bovine purine nucleoside phosphorylase complexed with phosphate · an experimental structure of the same protein · chain A against A, TM-score 0.97
  • 1A9O · Bovine purine nucleoside phosphorylase complexed with phosphate · an experimental structure of the same protein · chain A against A, TM-score 0.97
  • 1PBN · Purine nucleoside phosphorylase · an experimental structure of the same protein · chain A against A, TM-score 0.96
  • 1PBN · Purine nucleoside phosphorylase · an experimental structure of the same protein · chain A against A, TM-score 0.96

Analyse

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