MolNFT v1 · #18025 · protein

Purine nucleoside phosphorylase

1PBN: “Purine nucleoside phosphorylase”. X-ray diffraction, 1 pocket (best druggability 0.66). MolNFT v1 #18025 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1PBN
Type: protein
Length: 289 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Purine nucleoside phosphorylase
EC: 2.4.2.1
UniProt: P55859
Pockets: 1 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain · 30% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Purine nucleoside phosphorylase (EC 2.4.2.1)	protein	289	30% helix, 23% strand	P55859

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	309	0.66	0.82	45	empty

Compared structures

1PBN · Purine nucleoside phosphorylase · the same entry in another collection · chain A against A, TM-score 1.00
P55859 · AlphaFold monomer V2.0 prediction for purine nucleoside phosphorylase (P55859) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P55859
Elsewhere: RCSB PDB 1PBN · PDBe 1PBN · UniProt P55859

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