Research workbench
AlphaFold monomer V2.0 prediction for prostaglandin D2 receptor 2 (Q9Y5Y4)
Analyse AlphaFold monomer V2.0 prediction for prostaglandin D2 receptor 2 (Q9Y5Y4) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q9Y5Y4
- Type
- protein
- Length
- 395 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x013d37A39613599f6f82870f7F3B3DDe53b34038
- Molecule
- Prostaglandin D2 receptor 2
- UniProt
- Q9Y5Y4
- Pockets
- 3 · best druggability 0.77
Structure
1 distinct chain · 65% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Prostaglandin D2 receptor 2 | protein | 395 | 65% helix, 3% strand | Q9Y5Y4 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 474 | 0.77 | 0.85 | 38 | empty |
| 2 | 270 | 0.67 | 0.82 | 35 | empty |
| 3 | 101 | 0.40 | 0.76 | 22 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 7M8W · Xfel crystal structure of the prostaglandin D2 receptor CRTH2 in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.80
- 7M8W · XFEL crystal structure of the prostaglandin D2 receptor CRTH2 in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.80
- 6D26 · Crystal structure of the prostaglandin D2 receptor CRTH2 with fevipiprant · an experimental structure of the same protein · chain A against A, TM-score 0.79
- 6D26 · Crystal structure of the prostaglandin D2 receptor CRTH2 with fevipiprant · an experimental structure of the same protein · chain A against A, TM-score 0.79
- 6D27 · Crystal structure of the prostaglandin D2 receptor CRTH2 with CAY10471 · an experimental structure of the same protein · chain A against A, TM-score 0.78
- 6D27 · Crystal structure of the prostaglandin D2 receptor CRTH2 with CAY10471 · an experimental structure of the same protein · chain A against A, TM-score 0.78
- 9IYB · Cryo-EM Structure of the Prostaglandin D2 Receptor 2-PGD2 Coupled to G Protein · an experimental structure of the same protein · chain A against A, TM-score 0.73
- 8XXV · Cryo-EM Structure of the Prostaglandin D2 Receptor 2-indomethacin Coupled to G Protein · an experimental structure of the same protein · chain A against A, TM-score 0.73
- 8XXU · Cryo-EM Structure of the Prostaglandin D2 Receptor 2 Coupled to G Protein · an experimental structure of the same protein · chain A against A, TM-score 0.72
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y5Y4
- Elsewhere: UniProt Q9Y5Y4 · AlphaFold DB Q9Y5Y4
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