Research workbench
AlphaFold monomer V2.0 prediction for nucleoporin NUP157 (P40064)
Analyse AlphaFold monomer V2.0 prediction for nucleoporin NUP157 (P40064) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P40064
- Type
- protein
- Length
- 1,391 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x97EfFf2d74994e28D3b69b1503Bd9c292B2Df480
- Molecule
- Nucleoporin NUP157
- UniProt
- P40064
- Pockets
- 14 · best druggability 0.77
Structure
1 distinct chain · 43% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nucleoporin NUP157 | protein | 1391 | 43% helix, 15% strand | P40064 |
Pockets
14 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1050 | 0.77 | 0.79 | 86 | empty |
| 2 | 468 | 0.64 | 0.76 | 36 | empty |
| 3 | 228 | 0.62 | 0.82 | 28 | empty |
| 4 | 338 | 0.60 | 0.77 | 41 | empty |
| 5 | 71 | 0.52 | 0.85 | 19 | empty |
Compared structures
- 7WOO · Cryo-EM structure of the inner ring protomer of the saccharomyces cerevisiae nuclear pore… · an experimental structure of the same protein · chain A against C, TM-score 0.95
- 7WOO · Cryo-EM structure of the inner ring protomer of the Saccharomyces cerevisiae nuclear pore… · an experimental structure of the same protein · chain A against C, TM-score 0.95
- 7WOT · Cryo-EM structure of the inner ring monomer of the Saccharomyces cerevisiae nuclear pore… · an experimental structure of the same protein · chain A against O, TM-score 0.95
- 8TJ5 · Inner spoke ring of the yeast NPC · an experimental structure of the same protein · chain A against Z, TM-score 0.59
- 7N85 · Inner ring spoke from the isolated yeast NPC · an experimental structure of the same protein · chain A against 1, TM-score 0.49
- 7N9F · Structure of the in situ yeast NPC · an experimental structure of the same protein · chain A against Z, TM-score 0.49
- 4MHC · Crystal Structure of a Nucleoporin · an experimental structure of the same protein · chain A against A, TM-score 0.48
- 4MHC · Crystal structure of a nucleoporin · an experimental structure of the same protein · chain A against A, TM-score 0.48
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P40064
- Elsewhere: UniProt P40064 · AlphaFold DB P40064
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