UniProt P40064

Nucleoporin NUP157 (P40064)

Nucleoporin NUP157 (UniProt P40064): 6 experimental structures and 1 predicted model on GenesisL1, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: P40064
Protein: Nucleoporin NUP157
Experimental structures: 6
Predicted models: 1
Pockets: 17 · 3 records with a druggable one

Structures

7 records of P40064 in the MolNFT archive: 6 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
4MHC	Crystal Structure of a Nucleoporin	x-ray diffraction	A	—	—
4MHC	Crystal structure of a nucleoporin	x-ray diffraction	A	—	—
7N85	Inner ring spoke from the isolated yeast NPC	electron microscopy	1, Z	—	—
7N9F	Structure of the in situ yeast NPC	electron microscopy	1, Z	—	2 (best 0.83)
7WOO	Cryo-EM structure of the inner ring protomer of the Saccharomyces cerevisiae nuclear pore complex	electron microscopy	C	—	1 (best 0.77)
7WOO	Cryo-EM structure of the inner ring protomer of the saccharomyces cerevisiae nuclear pore complex	electron microscopy	C	—	—
P40064	AlphaFold monomer V2.0 prediction for nucleoporin NUP157 (P40064)	predicted	A	—	14 (best 0.77)

Experiment against prediction

7WOO chain C against the predicted model P40064: TM-score 1.00, RMSD 0.14 Å
7WOO chain C against the predicted model P40064: TM-score 1.00, RMSD 0.14 Å
4MHC chain A against the predicted model P40064: TM-score 0.99, RMSD 0.98 Å
4MHC chain A against the predicted model P40064: TM-score 0.99, RMSD 0.98 Å
7N85 chain 1 against the predicted model P40064: TM-score 0.59, RMSD 7.33 Å
7N9F chain Z against the predicted model P40064: TM-score 0.59, RMSD 7.41 Å
7N85 chain Z against the predicted model P40064: TM-score 0.59, RMSD 7.30 Å
7N9F chain 1 against the predicted model P40064: TM-score 0.57, RMSD 7.66 Å

Elsewhere

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