Research workbench
AlphaFold monomer V2.0 prediction for neutrophil cytosol factor 4 (Q15080)
Analyse AlphaFold monomer V2.0 prediction for neutrophil cytosol factor 4 (Q15080) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q15080
- Type
- protein
- Length
- 339 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x7FA92954d404a041504df5A47B6c56Cb346460FD
- Molecule
- Neutrophil cytosol factor 4
- UniProt
- Q15080
- Pockets
- 5 · best druggability 0.59
Structure
1 distinct chain · 27% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Neutrophil cytosol factor 4 | protein | 339 | 27% helix, 27% strand | Q15080 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 283 | 0.59 | 0.78 | 26 | empty |
| 2 | 177 | 0.52 | 0.78 | 24 | empty |
| 3 | 219 | 0.46 | 0.73 | 31 | empty |
| 4 | 109 | 0.38 | 0.75 | 25 | empty |
| 5 | 69 | 0.37 | 0.77 | 16 | empty |
Compared structures
- 2DYB · The crystal structure of human p40(phox) · an experimental structure of the same protein · chain A against A, TM-score 0.63
- 2DYB · The crystal structure of human P40(PHOX) · an experimental structure of the same protein · chain A against A, TM-score 0.63
- 1H6H · Structure of the PX domain from p40phox bound to phosphatidylinositol 3-phosphate · an experimental structure of the same protein · chain A against A, TM-score 0.41
- 1H6H · Structure of the px domain from P40PHOX bound to phosphatidylinositol 3-phosphate · an experimental structure of the same protein · chain A against A, TM-score 0.41
- 1OEY · Heterodimer of p40phox and p67phox PB1 domains from human NADPH oxidase · an experimental structure of the same protein · chain A against J, TM-score 0.30
- 1OEY · Heterodimer of P40PHOX and P67PHOX PB1 domains from human NADPH oxidase · an experimental structure of the same protein · chain A against J, TM-score 0.30
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q15080
- Elsewhere: UniProt Q15080 · AlphaFold DB Q15080
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