UniProt Q15080
Neutrophil cytosol factor 4 (Q15080)
Neutrophil cytosol factor 4 (UniProt Q15080): 12 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 35 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q15080
- Protein
- Neutrophil cytosol factor 4
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 35 · 4 records with a druggable one
Structures
13 records of Q15080 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1H6H | Structure of the PX domain from p40phox bound to phosphatidylinositol 3-phosphate | x-ray diffraction | A | PIB | 1 (best 0.54) |
| 1H6H | Structure of the px domain from P40PHOX bound to phosphatidylinositol 3-phosphate | x-ray diffraction | A | — | — |
| 1OEY | Heterodimer of p40phox and p67phox PB1 domains from human NADPH oxidase | x-ray diffraction | J, K, L, M | — | 15 (best 0.74) |
| 1OEY | Heterodimer of P40PHOX and P67PHOX PB1 domains from human NADPH oxidase | x-ray diffraction | J, K, L, M | — | — |
| 1W6X | SH3 domain of p40phox, component of the NADPH oxidase | x-ray diffraction | A, B | — | — |
| 1W6X | SH3 domain of P40PHOX, component of the NADPH oxidase | x-ray diffraction | A, B | — | — |
| 1W70 | SH3 domain of p40phox complexed with C-terminal polyProline region of p47phox | x-ray diffraction | A, B | SO4 | 1 (best 0.33) |
| 1W70 | SH3 domain of P40PHOX complexed with C-terminal polyproline region of P47PHOX | x-ray diffraction | A, B | — | — |
| 1Z9Q | Solution structure of SH3 domain of p40phox | solution nmr | A | — | — |
| 1Z9Q | Solution structure of SH3 domain of P40PHOX | solution nmr | A | — | — |
| 2DYB | The crystal structure of human p40(phox) | x-ray diffraction | A, B | — | 13 (best 0.69) |
| 2DYB | The crystal structure of human P40(PHOX) | x-ray diffraction | A, B | — | — |
| Q15080 | AlphaFold monomer V2.0 prediction for neutrophil cytosol factor 4 (Q15080) | predicted | A | — | 5 (best 0.59) |
Ligands
Experiment against prediction
- 1W6X chain A against the predicted model Q15080: TM-score 0.96, RMSD 0.57 Å
- 1W6X chain A against the predicted model Q15080: TM-score 0.96, RMSD 0.57 Å
- 1OEY chain M against the predicted model Q15080: TM-score 0.94, RMSD 1.07 Å
- 1OEY chain M against the predicted model Q15080: TM-score 0.94, RMSD 1.07 Å
- 1OEY chain L against the predicted model Q15080: TM-score 0.94, RMSD 1.10 Å
- 1OEY chain L against the predicted model Q15080: TM-score 0.94, RMSD 1.10 Å
- 1H6H chain A against the predicted model Q15080: TM-score 0.94, RMSD 1.38 Å
- 1H6H chain A against the predicted model Q15080: TM-score 0.94, RMSD 1.38 Å
- 1OEY chain K against the predicted model Q15080: TM-score 0.93, RMSD 1.28 Å
- 1OEY chain K against the predicted model Q15080: TM-score 0.93, RMSD 1.28 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.