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AlphaFold monomer V2.0 prediction for myogenesis-regulating glycosidase (Q6NSJ0)

Analyse AlphaFold monomer V2.0 prediction for myogenesis-regulating glycosidase (Q6NSJ0) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q6NSJ0
Type
protein
Length
714 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xf0Aa067888A3e900110FDD599F9Aa39D7DF7a484
Molecule
Myogenesis-regulating glycosidase
UniProt
Q6NSJ0
Pockets
7 · best druggability 0.65

Structure

1 distinct chain · 26% helix, 25% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AMyogenesis-regulating glycosidaseprotein71426% helix, 25% strandQ6NSJ0

Pockets

7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11480.650.8723empty
22030.550.7929empty
31230.410.7627empty
41280.410.7520empty
5970.370.7519empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

  • 7QQG · Crystal structure of myorg bound to 1-deoxygalactonojirimycin · an experimental structure of the same protein · chain A against B, TM-score 0.86
  • 7QQG · Crystal structure of MYORG bound to 1-deoxygalactonojirimycin · an experimental structure of the same protein · chain A against B, TM-score 0.86
  • 7QQH · Crystal structure of myorg (D520N) in complex with gal-A1,4-glc · an experimental structure of the same protein · chain A against B, TM-score 0.86
  • 7QQH · Crystal structure of MYORG (D520N) in complex with Gal-a1,4-Glc · an experimental structure of the same protein · chain A against B, TM-score 0.86
  • 7QQF · Crystal structure of unliganded myorg · an experimental structure of the same protein · chain A against C, TM-score 0.86
  • 7QQF · Crystal structure of unliganded MYORG · an experimental structure of the same protein · chain A against C, TM-score 0.86

Analyse

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