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UniProt Q6NSJ0

Myogenesis-regulating glycosidase (Q6NSJ0)

Myogenesis-regulating glycosidase (UniProt Q6NSJ0), EC 3.2.1.-: 6 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 67 pockets. Binding sites, druggability and experiment against prediction (TM-score)…

UniProt
Q6NSJ0
Protein
Myogenesis-regulating glycosidase
EC
3.2.1.-
Experimental structures
6
Predicted models
1
Ligands
5
Pockets
67 · 4 records with a druggable one

Structures

7 records of Q6NSJ0 in the MolNFT archive: 6 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
7QQFCrystal structure of unliganded MYORGx-ray diffractionA, B, C, DNAG, FUC20 (best 0.69)
7QQFCrystal structure of unliganded myorgx-ray diffractionA, B, C, DNAG, FUC—
7QQGCrystal structure of MYORG bound to 1-deoxygalactonojirimycinx-ray diffractionA, B, C, DNAG, FUC, DGJ20 (best 0.71)
7QQGCrystal structure of myorg bound to 1-deoxygalactonojirimycinx-ray diffractionA, B, C, DNAG, FUC, DGJ—
7QQHCrystal structure of MYORG (D520N) in complex with Gal-a1,4-Glcx-ray diffractionA, B, C, DNAG, BGC, GLA20 (best 0.66)
7QQHCrystal structure of myorg (D520N) in complex with gal-A1,4-glcx-ray diffractionA, B, C, DNAG, BGC, GLA—
Q6NSJ0AlphaFold monomer V2.0 prediction for myogenesis-regulating glycosidase (Q6NSJ0)predictedA—7 (best 0.65)

Ligands

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 6 records
  • FUC · alpha-L-fucopyranose · in 4 records
  • BGC · beta-D-glucopyranose · in 2 records
  • DGJ · (2R,3S,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol · in 2 records
  • GLA · alpha-D-galactopyranose · in 2 records

Experiment against prediction

Elsewhere

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