Research workbench
AlphaFold monomer V2.0 prediction for heat shock-related 70 kda protein 2 (P54652)
Analyse AlphaFold monomer V2.0 prediction for heat shock-related 70 kda protein 2… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P54652
- Type
- protein
- Length
- 639 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xABF9d7e9EFD71E8CB8E482eb0555A9ae669eD758
- Molecule
- Heat shock-related 70 kda protein 2
- UniProt
- P54652
- Pockets
- 8 · best druggability 0.74
Structure
1 distinct chain · 39% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Heat shock-related 70 kda protein 2 | protein | 639 | 39% helix, 27% strand | P54652 |
Pockets
8 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 204 | 0.74 | 0.90 | 36 | empty |
| 2 | 81 | 0.59 | 0.88 | 29 | empty |
| 3 | 216 | 0.59 | 0.80 | 38 | empty |
| 4 | 261 | 0.55 | 0.77 | 39 | empty |
| 5 | 78 | 0.51 | 0.84 | 16 | empty |
Compared structures
- 3I33 · Crystal structure of the human 70KDA heat shock protein 2 (HSP70-2) ATPase domain in… · an experimental structure of the same protein · chain A against A, TM-score 0.55
- 3I33 · Crystal structure of the human 70kDa heat shock protein 2 (Hsp70-2) ATPase domain in… · an experimental structure of the same protein · chain A against A, TM-score 0.55
- 5FPE · Structure of heat shock-related 70kDA protein 2 with small-molecule ligand… · an experimental structure of the same protein · chain A against B, TM-score 0.53
- 5FPE · Structure of heat shock-related 70KDA protein 2 with small- molecule ligand… · an experimental structure of the same protein · chain A against B, TM-score 0.53
- 4FSV · Crystal structure of a heat shock 70kDa protein 2 (HSPA2) from Homo sapiens at 1.80 A… · an experimental structure of the same protein · chain A against A, TM-score 0.53
- 4FSV · Crystal structure of a heat shock 70KDA protein 2 (HSPA2) from homo sapiens at 1.80 a… · an experimental structure of the same protein · chain A against A, TM-score 0.53
- 5FPM · Structure of heat shock-related 70kDA protein 2 with small-molecule ligand… · an experimental structure of the same protein · chain A against B, TM-score 0.53
- 5FPM · Structure of heat shock-related 70KDA protein 2 with small- molecule ligand… · an experimental structure of the same protein · chain A against B, TM-score 0.53
- 5FPN · Structure of heat shock-related 70kDA protein 2 with small-molecule ligand… · an experimental structure of the same protein · chain A against A, TM-score 0.53
- 5FPN · Structure of heat shock-related 70KDA protein 2 with small- molecule ligand… · an experimental structure of the same protein · chain A against A, TM-score 0.53
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P54652
- Elsewhere: UniProt P54652 · AlphaFold DB P54652
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