MolNFT v1 · #91962 · protein
Crystal structure of a heat shock 70KDA protein 2 (HSPA2) from homo sapiens at 1.80 a resolution
4FSV · Heat shock-related 70 kda protein 2: “Crystal structure of a heat shock 70KDA protein 2 (HSPA2) from homo sapiens at 1.80 a resolution”. X-ray diffraction, 1 pocket (best druggability 0.74). MolNFT v1 #91962 on GenesisL1: 3D…
- PDB
- 4FSV
- Type
- protein
- Length
- 380 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Heat shock-related 70 kda protein 2
- UniProt
- P54652
- Pockets
- 1 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Heat shock-related 70 kda protein 2 | protein | 380 | 42% helix, 29% strand | P54652 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 756 | 0.74 | 0.79 | 66 | empty |
Modifications
Observed in the structure: 5 modified (engineered).
Compared structures
- 4FSV · Crystal structure of a heat shock 70kDa protein 2 (HSPA2) from Homo sapiens at 1.80 A… · the same entry in another collection · chain A against A, TM-score 1.00
- P54652 · AlphaFold monomer V2.0 prediction for heat shock-related 70 kda protein 2 (P54652) · a predicted model of the same protein · chain A against A, TM-score 0.85
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P54652
- Elsewhere: RCSB PDB 4FSV · PDBe 4FSV · UniProt P54652
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