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Crystal structure of a heat shock 70KDA protein 2 (HSPA2) from homo sapiens at 1.80 a resolution

Analyse Crystal structure of a heat shock 70KDA protein 2 (HSPA2) from homo sapiens at… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4FSV
Type: protein
Length: 380 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Heat shock-related 70 kda protein 2
UniProt: P54652
Pockets: 1 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Heat shock-related 70 kda protein 2	protein	380	42% helix, 29% strand	P54652

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	756	0.74	0.79	66	empty

Modifications

Observed in the structure: 5 modified (engineered).

Compared structures

4FSV · Crystal structure of a heat shock 70kDa protein 2 (HSPA2) from Homo sapiens at 1.80 A… · the same entry in another collection · chain A against A, TM-score 1.00
P54652 · AlphaFold monomer V2.0 prediction for heat shock-related 70 kda protein 2 (P54652) · a predicted model of the same protein · chain A against A, TM-score 0.85

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P54652
Elsewhere: RCSB PDB 4FSV · PDBe 4FSV · UniProt P54652

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