Research workbench
AlphaFold monomer V2.0 prediction for tyrosine-protein kinase FES/FPS (P07332)
Analyse AlphaFold monomer V2.0 prediction for tyrosine-protein kinase FES/FPS (P07332) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P07332
- Type
- protein
- Length
- 822 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xC1a2331080F9f293f74510f6a0ea59C01Ef69FAB
- Molecule
- Tyrosine-protein kinase FES/FPS
- UniProt
- P07332
- Pockets
- 7 · best druggability 0.56
Structure
1 distinct chain · 56% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tyrosine-protein kinase FES/FPS | protein | 822 | 56% helix, 10% strand | P07332 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 207 | 0.56 | 0.79 | 26 | empty |
| 2 | 104 | 0.54 | 0.83 | 16 | empty |
| 3 | 117 | 0.50 | 0.81 | 19 | empty |
| 4 | 57 | 0.44 | 0.83 | 15 | empty |
| 5 | 95 | 0.33 | 0.73 | 14 | empty |
Compared structures
- 3BKB · Crystal structure of human feline sarcoma viral oncogene homologue (V- fes) · an experimental structure of the same protein · chain A against A, TM-score 0.45
- 3BKB · Crystal structure of human Feline Sarcoma Viral Oncogene Homologue (v-FES) · an experimental structure of the same protein · chain A against A, TM-score 0.45
- 6JMF · Crystal structure of human tyrosine-protein kinase FES/FPS in complex with compound 4 · an experimental structure of the same protein · chain A against A, TM-score 0.45
- 6JMF · Crystal structure of human tyrosine-protein kinase Fes/Fps in complex with compound 4 · an experimental structure of the same protein · chain A against A, TM-score 0.45
- 8XKP · Crystal structure of human tyrosine-protein kinase Fes/Fps in complex with compound 17c · an experimental structure of the same protein · chain A against A, TM-score 0.45
- 4E93 · Crystal structure of human Feline Sarcoma Viral Oncogene Homologue (v-FES)in complex with… · an experimental structure of the same protein · chain A against A, TM-score 0.43
- 4E93 · Crystal structure of human feline sarcoma viral oncogene homologue (V- FES)IN complex… · an experimental structure of the same protein · chain A against A, TM-score 0.43
- 4DYL · F-bar domain of human fes tyrosine kinase · an experimental structure of the same protein · chain A against A, TM-score 0.43
- 4DYL · F-BAR domain of human FES tyrosine kinase · an experimental structure of the same protein · chain A against A, TM-score 0.43
- 3CBL · Crystal structure of human feline sarcoma viral oncogene homologue (v-FES) in complex… · an experimental structure of the same protein · chain A against A, TM-score 0.43
- 3CBL · Crystal structure of human feline sarcoma viral oncogene homologue (V- fes) in complex… · an experimental structure of the same protein · chain A against A, TM-score 0.43
- 8X2T · The Crystal Structure of FES from Biortus. · an experimental structure of the same protein · chain A against A, TM-score 0.43
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07332
- Elsewhere: UniProt P07332 · AlphaFold DB P07332
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