UniProt Q9V2F3
DNA polymerase II small subunit (Q9V2F3)
DNA polymerase II small subunit (UniProt Q9V2F3), EC 2.7.7.7, 3.1.11.1: 11 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 35 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9V2F3
- Protein
- DNA polymerase II small subunit
- EC
- 2.7.7.7, 3.1.11.1
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 35 · 6 records with a druggable one
Structures
12 records of Q9V2F3 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5IHE | D-family DNA polymerase - DP1 subunit (3'-5' proof-reading exonuclease) | x-ray diffraction | A, B | D5M, FE, ZN, CA | — |
| 5IHE | D-family DNA polymerase - DP1 subunit (3'-5' proof-reading exonuclease) | x-ray diffraction | A, B | — | — |
| 6HMF | D-family DNA polymerase - DP1 subunit (3'-5' proof-reading exonuclease) H451 proof-reading… | x-ray diffraction | A, B | FE, ZN, CA | — |
| 6HMS | Cryo-EM MAP of DNA polymerase D from pyrococcus abyssi in complex with DNA | electron microscopy | A | ZN | — |
| 6T8H | Cryo-EM structure of the DNA-bound PolD-PCNA processive complex from P. abyssi | electron microscopy | A | FE, ZN | 7 (best 0.81) |
| 6T8H | Cryo-EM structure of the DNA-bound pold-PCNA processive complex from P. abyssi | electron microscopy | A | FE, ZN | — |
| 8PPT | Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate… | electron microscopy | A | MG | 6 (best 0.81) |
| 8PPU | Pyrococcus abyssi DNA polymerase D (PolD) in its editing mode bound to a primer/template substrate… | electron microscopy | A | MG | 5 (best 0.79) |
| 8PPV | Intermediate conformer of Pyrococcus abyssi DNA polymerase D (PolD) bound to a primer/template… | electron microscopy | A | MG | 4 (best 0.82) |
| 9F29 | Pyrococcus abyssi PolD in complex with Rpa2 winged-helix domain class 1 (composite map) | electron microscopy | A | FE | 7 (best 0.74) |
| 9F2A | Pyrococcus abyssi PolD in complex with Rpa2 winged-helix domain class 2 (composite map) | electron microscopy | A | FE | 6 (best 0.74) |
| Q9V2F3 | AlphaFold monomer V2.0 prediction for DNA polymerase II small subunit (Q9V2F3) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6T8H chain A against the predicted model Q9V2F3: TM-score 1.00, RMSD 0.51 Å
- 6T8H chain A against the predicted model Q9V2F3: TM-score 1.00, RMSD 0.51 Å
- 5IHE chain A against the predicted model Q9V2F3: TM-score 0.99, RMSD 0.61 Å
- 5IHE chain A against the predicted model Q9V2F3: TM-score 0.99, RMSD 0.61 Å
- 6HMF chain A against the predicted model Q9V2F3: TM-score 0.99, RMSD 0.62 Å
- 6HMF chain B against the predicted model Q9V2F3: TM-score 0.99, RMSD 1.12 Å
- 8PPT chain A against the predicted model Q9V2F3: TM-score 0.99, RMSD 0.87 Å
- 5IHE chain B against the predicted model Q9V2F3: TM-score 0.99, RMSD 1.12 Å
- 5IHE chain B against the predicted model Q9V2F3: TM-score 0.99, RMSD 1.12 Å
- 8PPU chain A against the predicted model Q9V2F3: TM-score 0.99, RMSD 0.92 Å
Elsewhere
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