UniProt Q9UZK7
Probable translation initiation factor IF-2 (Q9UZK7)
Probable translation initiation factor IF-2 (UniProt Q9UZK7): 9 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 25 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q9UZK7
- Protein
- Probable translation initiation factor IF-2
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 25 · 3 records with a druggable one
Structures
10 records of Q9UZK7 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7YYP | Structure of aIF5B from Pyrococcus abyssi complexed with GDP | x-ray diffraction | A | GDP, NO3 | 6 (best 0.52) |
| 7YZN | Structure of C-terminally truncated aIF5B from Pyrococcus abyssi complexed with GTP | x-ray diffraction | A | MG, GTP, NA | 7 (best 0.57) |
| 7YZN | Structure of C-terminally truncated AIF5B from pyrococcus abyssi complexed with GTP | x-ray diffraction | A | MG, GTP, NA | — |
| 7ZAG | Cryo-EM structure of a Pyrococcus abyssi 30S bound to Met-initiator tRNA,mRNA, aIF1A and the… | electron microscopy | 7 | MET | — |
| 7ZAG | Cryo-EM structure of a pyrococcus abyssi 30S bound to met-initiator TRNA,MRNA, AIF1A and the… | electron microscopy | 7 | MET | — |
| 7ZAH | Cryo-EM structure of a Pyrococcus abyssi 30S bound to Met-initiator tRNA, mRNA, aIF1A and aIF5B | electron microscopy | 7 | MET, GNP, MG | — |
| 7ZAH | Cryo-EM structure of an archaeal AIF5B bound to the ssu translation initiation complex | electron microscopy | 7 | MET, GNP, MG | — |
| 7ZKI | Cryo-EM structure of aIF1A:aIF5B:Met-tRNAiMet complex from a Pyrococcus abyssi 30S initiation… | electron microscopy | 7 | MET, GNP, MG | 12 (best 0.68) |
| 7ZKI | Cryo-EM structure of AIF1A:AIF5B:MET-trnaimet complex from a pyrococcus abyssi 30S initiation… | electron microscopy | 7 | MET, GNP, MG | — |
| Q9UZK7 | AlphaFold monomer V2.0 prediction for probable translation initiation factor if-2 (Q9UZK7) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7ZAG chain 7 against the predicted model Q9UZK7: TM-score 0.93, RMSD 1.18 Å
- 7ZAG chain 7 against the predicted model Q9UZK7: TM-score 0.93, RMSD 1.18 Å
- 7YYP chain A against the predicted model Q9UZK7: TM-score 0.74, RMSD 5.29 Å
- 7YZN chain A against the predicted model Q9UZK7: TM-score 0.70, RMSD 5.27 Å
- 7YZN chain A against the predicted model Q9UZK7: TM-score 0.70, RMSD 5.27 Å
- 7ZAH chain 7 against the predicted model Q9UZK7: TM-score 0.68, RMSD 5.57 Å
- 7ZAH chain 7 against the predicted model Q9UZK7: TM-score 0.68, RMSD 5.57 Å
- 7ZKI chain 7 against the predicted model Q9UZK7: TM-score 0.68, RMSD 5.57 Å
- 7ZKI chain 7 against the predicted model Q9UZK7: TM-score 0.68, RMSD 5.57 Å
Elsewhere
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