UniProt Q9UL25
Ras-related protein Rab-21 (Q9UL25)
Ras-related protein Rab-21 (UniProt Q9UL25): 10 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9UL25
- Protein
- Ras-related protein Rab-21
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 11 · 4 records with a druggable one
Structures
11 records of Q9UL25 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1YZT | GppNHp-Bound Rab21 GTPase at 2.05 A Resolution | x-ray diffraction | A, B | MG, GNP | 2 (best 0.57) |
| 1YZT | Gppnhp-bound RAB21 GTPase at 2.05 a resolution | x-ray diffraction | A, B | — | — |
| 1YZU | GppNHp-Bound Rab21 GTPase at 2.50 A Resolution | x-ray diffraction | A, B | MG, GNP | 2 (best 0.54) |
| 1YZU | Gppnhp-bound RAB21 GTPase at 2.50 a resolution | x-ray diffraction | A, B | — | — |
| 1Z08 | GppNHp-Bound Rab21 Q53G mutant GTPase | x-ray diffraction | A, B, C, D | MG, GNP | 4 (best 0.56) |
| 1Z08 | Gppnhp-bound RAB21 Q53G mutant GTPase | x-ray diffraction | A, B, C, D | — | — |
| 1Z0I | GDP-Bound Rab21 GTPase | x-ray diffraction | A | MG, GDP | 2 (best 0.41) |
| 1Z0I | GDP-bound RAB21 GTPase | x-ray diffraction | A | — | — |
| 2OT3 | Crystal structure of rabex-5 VPS9 domain in complex with nucleotide free RAB21 | x-ray diffraction | B | — | — |
| 2OT3 | Crystal structure of rabex-5 VPS9 domain in complex with nucleotide free RAB21 | x-ray diffraction | B | — | — |
| Q9UL25 | AlphaFold monomer V2.0 prediction for RAS-related protein rab-21 (Q9UL25) | predicted | A | — | 1 (best 0.55) |
Ligands
Experiment against prediction
- 1Z08 chain A against the predicted model Q9UL25: TM-score 0.99, RMSD 0.58 Å
- 1Z08 chain A against the predicted model Q9UL25: TM-score 0.99, RMSD 0.58 Å
- 1Z08 chain B against the predicted model Q9UL25: TM-score 0.98, RMSD 0.65 Å
- 1Z08 chain B against the predicted model Q9UL25: TM-score 0.98, RMSD 0.65 Å
- 1YZT chain B against the predicted model Q9UL25: TM-score 0.98, RMSD 0.66 Å
- 1YZT chain B against the predicted model Q9UL25: TM-score 0.98, RMSD 0.66 Å
- 1YZT chain A against the predicted model Q9UL25: TM-score 0.98, RMSD 0.72 Å
- 1YZT chain A against the predicted model Q9UL25: TM-score 0.98, RMSD 0.72 Å
- 1Z08 chain D against the predicted model Q9UL25: TM-score 0.96, RMSD 1.08 Å
- 1Z08 chain D against the predicted model Q9UL25: TM-score 0.96, RMSD 1.08 Å
Elsewhere
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