UniProt Q9UJY5
ADP-ribosylation factor binding protein GGA1 (Q9UJY5)
ADP-ribosylation factor binding protein GGA1 (UniProt Q9UJY5): 40 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q9UJY5
- Protein
- ADP-ribosylation factor binding protein GGA1
- Experimental structures
- 40
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 18 · 5 records with a druggable one
Structures
41 records of Q9UJY5 in the MolNFT archive: 40 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1J2J | Crystal structure of GGA1 GAT N-terminal region in complex with ARF1 GTP form | x-ray diffraction | B | IOD | — |
| 1J2J | Crystal structure of GGA1 gat N-terminal region in complex with ARF1 GTP form | x-ray diffraction | B | — | — |
| 1JWF | Crystal Structure of human GGA1 VHS domain. | x-ray diffraction | A | — | — |
| 1JWF | Crystal structure of human GGA1 vhs domain. | x-ray diffraction | A | — | — |
| 1JWG | VHS Domain of human GGA1 complexed with cation-independent M6PR C-terminal Peptide | x-ray diffraction | A, B | IOD | 2 (best 0.58) |
| 1JWG | Vhs domain of human GGA1 complexed with cation-independent M6PR C-terminal peptide | x-ray diffraction | A, B | — | — |
| 1NA8 | Crystal structure of ADP-ribosylation factor binding protein GGA1 | x-ray diffraction | A, B | — | — |
| 1NA8 | Crystal structure of ADP-ribosylation factor binding protein GGA1 | x-ray diffraction | A, B | — | — |
| 1NAF | Crystal structure of the human GGA1 GAT domain | x-ray diffraction | A | — | 1 (best 0.30) |
| 1NAF | Crystal structure of the human GGA1 gat domain | x-ray diffraction | A | — | — |
| 1NWM | GAT domain of human GGA1 | x-ray diffraction | X | — | 1 (best 0.38) |
| 1NWM | Gat domain of human GGA1 | x-ray diffraction | X | — | — |
| 1O3X | Crystal structure of human GGA1 GAT domain | x-ray diffraction | A | — | — |
| 1O3X | Crystal structure of human GGA1 gat domain | x-ray diffraction | A | — | — |
| 1OM9 | Structure of the GGA1-appendage in complex with the p56 binding peptide | x-ray diffraction | A, B | — | 4 (best 0.53) |
| 1OM9 | Structure of the GGA1-appendage in complex with the P56 binding peptide | x-ray diffraction | A, B | — | — |
| 1OXZ | Crystal Structure of the Human GGA1 GAT domain | x-ray diffraction | A | — | — |
| 1OXZ | Crystal structure of the human GGA1 gat domain | x-ray diffraction | A | — | — |
| 1PY1 | Complex of GGA1-VHS domain and beta-secretase C-terminal phosphopeptide | x-ray diffraction | A, B, C, D | — | 4 (best 0.73) |
| 1PY1 | Complex of GGA1-vhs domain and beta-secretase C-terminal phosphopeptide | x-ray diffraction | A, B, C, D | — | — |
| 1UJJ | VHS domain of human GGA1 complexed with C-terminal peptide from BACE | x-ray diffraction | A, B | — | 2 (best 0.51) |
| 1UJJ | Vhs domain of human GGA1 complexed with C-terminal peptide from bace | x-ray diffraction | A, B | — | — |
| 1UJK | VHS domain of human GGA1 complexed with C-terminal phosphopeptide from BACE | x-ray diffraction | A, B | IOD | 2 (best 0.50) |
| 1UJK | Vhs domain of human GGA1 complexed with C-terminal phosphopeptide from bace | x-ray diffraction | A, B | — | — |
| 1X79 | Crystal structure of human GGA1 GAT domain complexed with the GAT-binding domain of Rabaptin5 | x-ray diffraction | A | — | 2 (best 0.34) |
| 1X79 | Crystal structure of human GGA1 gat domain complexed with the gat- binding domain of RABAPTIN5 | x-ray diffraction | A | — | — |
| 2DWX | Co-crystal Structure Analysis of GGA1-GAE with the WNSF motif | x-ray diffraction | A, B, C, D, P, Q | — | — |
| 2DWX | Co-crystal structure analysis of GGA1-gae with the wnsf motif | x-ray diffraction | A, B, C, D, P, Q | — | — |
| 2DWY | Crystal Structure Analysis of GGA1-GAE | x-ray diffraction | A, B, C, D | — | — |
| 2DWY | Crystal structure analysis of GGA1-gae | x-ray diffraction | A, B, C, D | — | — |
| 3G2S | VHS Domain of human GGA1 complexed with SorLA C-terminal Peptide | x-ray diffraction | A, B | — | — |
| 3G2S | Vhs domain of human GGA1 complexed with sorla C-terminal peptide | x-ray diffraction | A, B | — | — |
| 3G2T | VHS Domain of human GGA1 complexed with SorLA C-terminal Phosphopeptide | x-ray diffraction | A, B | — | — |
| 3G2T | Vhs domain of human GGA1 complexed with sorla C-terminal phosphopeptide | x-ray diffraction | A, B | — | — |
| 3G2U | VHS Domain of human GGA1 complexed with Sotilin C-terminal Peptide | x-ray diffraction | A, B | — | — |
| 3G2U | Vhs domain of human GGA1 complexed with sotilin C-terminal peptide | x-ray diffraction | A, B | — | — |
| 3G2V | VHS Domain of human GGA1 complexed with Sotilin C-terminal Phosphopeptide | x-ray diffraction | A, B | — | — |
| 3G2V | Vhs domain of human GGA1 complexed with sotilin C-terminal phosphopeptide | x-ray diffraction | A, B | — | — |
| 3G2W | VHS Domain of human GGA1 complexed with a DXXLL hinge peptide | x-ray diffraction | A, B, C, D | — | — |
| 3G2W | Vhs domain of human GGA1 complexed with a dxxll hinge peptide | x-ray diffraction | A, B, C, D | — | — |
| Q9UJY5 | AlphaFold monomer V2.0 prediction for ADP-ribosylation factor-binding protein GGA1 (Q9UJY5) | predicted | A | — | — |
Ligands
- IOD · Iodide ion · in 3 records
Experiment against prediction
- 3G2W chain A against the predicted model Q9UJY5: TM-score 0.99, RMSD 0.44 Å
- 3G2W chain A against the predicted model Q9UJY5: TM-score 0.99, RMSD 0.44 Å
- 1PY1 chain A against the predicted model Q9UJY5: TM-score 0.99, RMSD 0.45 Å
- 1PY1 chain A against the predicted model Q9UJY5: TM-score 0.99, RMSD 0.45 Å
- 1UJK chain B against the predicted model Q9UJY5: TM-score 0.99, RMSD 0.49 Å
- 1UJK chain B against the predicted model Q9UJY5: TM-score 0.99, RMSD 0.49 Å
- 3G2V chain A against the predicted model Q9UJY5: TM-score 0.99, RMSD 0.50 Å
- 3G2V chain A against the predicted model Q9UJY5: TM-score 0.99, RMSD 0.50 Å
- 1PY1 chain C against the predicted model Q9UJY5: TM-score 0.99, RMSD 0.49 Å
- 1PY1 chain C against the predicted model Q9UJY5: TM-score 0.99, RMSD 0.49 Å
Elsewhere
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