MolNFT v1 · #15620 · protein

Crystal structure of the human GGA1 gat domain

1NAF · ADP-ribosylation factor binding protein GGA1: “Crystal structure of the human GGA1 gat domain”. X-ray diffraction, 1 pocket (best druggability 0.30). MolNFT v1 #15620 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1NAF
Type: protein
Length: 124 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ADP-ribosylation factor binding protein GGA1
UniProt: Q9UJY5
Pockets: 1 · best druggability 0.30

Structure

x-ray diffraction · 1 distinct chain · 82% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ADP-ribosylation factor binding protein GGA1	protein	124	82% helix, 0% strand	Q9UJY5

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	63	0.30	0.74	16	empty

Modifications

Observed in the structure: 7 modified (engineered).

Compared structures

1NAF · Crystal structure of the human GGA1 GAT domain · the same entry in another collection · chain A against A, TM-score 1.00
Q9UJY5 · AlphaFold monomer V2.0 prediction for ADP-ribosylation factor-binding protein GGA1… · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9UJY5
Elsewhere: RCSB PDB 1NAF · PDBe 1NAF · UniProt Q9UJY5

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