UniProt Q9TV66
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (Q9TV66)
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4,Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 (UniProt Q9TV66): 6 experimental structures and 1 predicted model on…
- UniProt
- Q9TV66
- Protein
- Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel…
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 60 · 3 records with a druggable one
Structures
7 records of Q9TV66 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7NMN | Rabbit HCN4 stabilised in amphipol A8-35 | electron microscopy | A, B, C, D | — | 20 (best 0.87) |
| 7NMN | Rabbit HCN4 stabilised in amphipol A8-35 | electron microscopy | A, B, C, D | — | — |
| 7NP3 | cAMP-free rabbit HCN4 stabilized in LMNG-CHS detergent mixture | electron microscopy | A, B, C, D | — | 20 (best 0.87) |
| 7NP3 | Camp-free rabbit HCN4 stabilized in lmng-chs detergent mixture | electron microscopy | A, B, C, D | — | — |
| 7NP4 | cAMP-bound rabbit HCN4 stabilized in LMNG-CHS detergent mixture | electron microscopy | A, B, C, D | CMP | 20 (best 0.82) |
| 7NP4 | Camp-bound rabbit HCN4 stabilized in lmng-chs detergent mixture | electron microscopy | A, B, C, D | CMP | — |
| Q9TV66 | AlphaFold monomer V2.0 prediction for POTASSIUM/SODIUM hyperpolarization-activated cyclic… | predicted | A | — | — |
Ligands
- CMP · Adenosine-3',5'-cyclic-monophosphate · in 2 records
Experiment against prediction
- 7NP4 chain B against the predicted model Q9TV66: TM-score 0.97, RMSD 1.36 Å
- 7NP4 chain B against the predicted model Q9TV66: TM-score 0.97, RMSD 1.36 Å
- 7NP4 chain C against the predicted model Q9TV66: TM-score 0.97, RMSD 1.36 Å
- 7NP4 chain C against the predicted model Q9TV66: TM-score 0.97, RMSD 1.36 Å
- 7NP4 chain A against the predicted model Q9TV66: TM-score 0.97, RMSD 1.36 Å
- 7NP4 chain A against the predicted model Q9TV66: TM-score 0.97, RMSD 1.36 Å
- 7NP4 chain D against the predicted model Q9TV66: TM-score 0.97, RMSD 1.36 Å
- 7NP4 chain D against the predicted model Q9TV66: TM-score 0.97, RMSD 1.36 Å
- 7NP3 chain C against the predicted model Q9TV66: TM-score 0.90, RMSD 2.88 Å
- 7NP3 chain C against the predicted model Q9TV66: TM-score 0.90, RMSD 2.88 Å
Elsewhere
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