UniProt Q9RXJ5

50S ribosomal protein L16 (Q9RXJ5)

50S ribosomal protein L16 (UniProt Q9RXJ5): 53 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 76 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q9RXJ5
Protein: 50S ribosomal protein L16
Experimental structures: 53
Predicted models: 1
Ligands: 3
Pockets: 76 · 50 records with a druggable one

Structures

54 records of Q9RXJ5 in the MolNFT archive: 53 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
1NJM	The crystal structure of the 50S Large ribosomal subunit from Deinococcus radiodurans complexed…	x-ray diffraction	K	—	2 (best 0.86)
1NJM	The crystal structure of the 50S large ribosomal subunit from deinococcus radiodurans complexed…	x-ray diffraction	K	—	2 (best 0.86)
1NJP	The crystal structure of the 50S Large ribosomal subunit from Deinococcus radiodurans complexed…	x-ray diffraction	K	—	2 (best 0.86)
1NJP	The crystal structure of the 50S large ribosomal subunit from deinococcus radiodurans complexed…	x-ray diffraction	K	—	2 (best 0.86)
1NKW	Crystal Structure Of The Large Ribosomal Subunit From Deinococcus Radiodurans	x-ray diffraction	K	—	1 (best 0.82)
1NKW	Crystal structure of the large ribosomal subunit from deinococcus radiodurans	x-ray diffraction	K	—	1 (best 0.82)
1NWX	Complex of the large ribosomal subunit from deinococcus radiodurans with abt-773	x-ray diffraction	K	—	1 (best 0.79)
1NWX	Complex of the large ribosomal subunit from deinococcus radiodurans with abt-773	x-ray diffraction	K	—	1 (best 0.79)
1NWY	Complex of the large ribosomal subunit from deinococcus radiodurans with azithromycin	x-ray diffraction	K	—	1 (best 0.82)
1NWY	Complex of the large ribosomal subunit from deinococcus radiodurans with azithromycin	x-ray diffraction	K	—	1 (best 0.82)
1SM1	Complex of the large ribosomal subunit from deinococcus radiodurans with quinupristin and…	x-ray diffraction	K	—	1 (best 0.78)
1SM1	Complex of the large ribosomal subunit from deinococcus radiodurans with quinupristin and…	x-ray diffraction	K	—	1 (best 0.78)
1XBP	Inhibition of peptide bond formation by pleuromutilins: The structure of the 50S ribosomal subunit…	x-ray diffraction	K	—	1 (best 0.75)
1XBP	Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit…	x-ray diffraction	K	—	1 (best 0.75)
1Y69	RRF domain I in complex with the 50S ribosomal subunit from Deinococcus radiodurans	x-ray diffraction	K	—	2 (best 0.88)
1Y69	Rrf domain I in complex with the 50S ribosomal subunit from deinococcus radiodurans	x-ray diffraction	K	—	2 (best 0.88)
2ZJP	Thiopeptide antibiotic Nosiheptide bound to the large ribosomal subunit of Deinococcus radiodurans	x-ray diffraction	J	MG	2 (best 0.86)
2ZJP	Thiopeptide antibiotic nosiheptide bound to the large ribosomal subunit of deinococcus radiodurans	x-ray diffraction	J	MG	2 (best 0.86)
2ZJQ	Interaction of L7 with L11 induced by Microccocin binding to the Deinococcus radiodurans 50S subunit	x-ray diffraction	J	—	2 (best 0.86)
2ZJQ	Interaction of L7 with L11 induced by microccocin binding to the deinococcus radiodurans 50S subunit	x-ray diffraction	J	—	2 (best 0.86)
2ZJR	Refined native structure of the large ribosomal subunit (50S) from Deinococcus radiodurans	x-ray diffraction	J	—	2 (best 0.85)
2ZJR	Refined native structure of the large ribosomal subunit (50S) from deinococcus radiodurans	x-ray diffraction	J	—	2 (best 0.85)
3CF5	Thiopeptide antibiotic Thiostrepton bound to the large ribosomal subunit of Deinococcus radiodurans	x-ray diffraction	J	—	1 (best 0.83)
3CF5	Thiopeptide antibiotic thiostrepton bound to the large ribosomal subunit of deinococcus radiodurans	x-ray diffraction	J	—	1 (best 0.83)
3DLL	The oxazolidi antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA…	x-ray diffraction	J	—	2 (best 0.84)
3DLL	The oxazolidinone antibiotics perturb the ribosomal peptidyl- transferase center and effect tRNA…	x-ray diffraction	J	—	2 (best 0.84)
3PIO	Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the…	x-ray diffraction	J	—	1 (best 0.87)
3PIO	Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the…	x-ray diffraction	J	—	1 (best 0.87)
3PIP	Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the…	x-ray diffraction	J	—	2 (best 0.86)
3PIP	Crystal structure of the synergistic antibiotic pair lankamycin and lankacidin in complex with the…	x-ray diffraction	J	—	2 (best 0.86)
4IO9	Crystal structure of compound 4d bound to large ribosomal subunit (50S) from Deinococcus radiodurans	x-ray diffraction	J	MG	1 (best 0.86)
4IO9	Crystal structure of compound 4D bound to large ribosomal subunit (50S) from deinococcus radiodurans	x-ray diffraction	J	MG	1 (best 0.86)
4IOA	Crystal structure of compound 4e bound to large ribosomal subunit (50S) from Deinococcus radiodurans	x-ray diffraction	J	—	1 (best 0.88)
4IOA	Crystal structure of compound 4E bound to large ribosomal subunit (50S) from deinococcus radiodurans	x-ray diffraction	J	—	1 (best 0.88)
4IOC	Crystal structure of compound 4f bound to large ribosomal subunit (50S) from Deinococcus radiodurans	x-ray diffraction	J	MG	3 (best 0.84)
4IOC	Crystal structure of compound 4F bound to large ribosomal subunit (50S) from deinococcus radiodurans	x-ray diffraction	J	MG	3 (best 0.84)
4U67	Crystal structure of the large ribosomal subunit (50S) of Deinococcus radiodurans containing a…	x-ray diffraction	J	—	2 (best 0.86)
4U67	Crystal structure of the large ribosomal subunit (50S) of deinococcus radiodurans containing a…	x-ray diffraction	J	—	2 (best 0.86)
4WFN	Crystal structure of the large ribosomal subunit (50S) of deinococcus radiodurans containing a…	x-ray diffraction	J	—	2 (best 0.86)
5DM6	Crystal structure of the 50S ribosomal subunit from Deinococcus radiodurans	x-ray diffraction	J	—	1 (best 0.87)
5DM6	Crystal structure of the 50S ribosomal subunit from deinococcus radiodurans	x-ray diffraction	J	—	1 (best 0.87)
5DM7	Crystal structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with…	x-ray diffraction	J	—	1 (best 0.82)
5DM7	Crystal structure of the 50S ribosomal subunit from deinococcus radiodurans in complex with…	x-ray diffraction	J	—	1 (best 0.82)
5JVG	The large ribosomal subunit from Deinococcus radiodurans in complex with avilamycin	x-ray diffraction	J	6NO, MG	2 (best 0.83)
5JVG	The large ribosomal subunit from deinococcus radiodurans in complex with avilamycin	x-ray diffraction	J	6NO, MG	2 (best 0.83)
5JVH	The crystal structure large ribosomal subunit (50S) of Deinococcus radiodurans in complex with…	x-ray diffraction	J	6O1	1 (best 0.87)
5JVH	The crystal structure large ribosomal subunit (50S) of deinococcus radiodurans in complex with…	x-ray diffraction	J	6O1	1 (best 0.87)
7A0R	50S Deinococcus radiodurans ribosome bounded with mycinamicin I	x-ray diffraction	J	MG	1 (best 0.82)
7A0R	50S deinococcus radiodurans ribosome bounded with mycinamicin I	x-ray diffraction	J	MG	—
7A0S	50S Deinococcus radiodurans ribosome bounded with mycinamicin I	x-ray diffraction	J	MG	2 (best 0.85)
7A0S	50S deinococcus radiodurans ribosome bounded with mycinamicin I	x-ray diffraction	J	MG	—
7A18	50S Deinococcus radiodurans ribosome bounded with mycinamicin IV	x-ray diffraction	J	MG	1 (best 0.82)
7A18	50S deinococcus radiodurans ribosome bounded with mycinamicin IV	x-ray diffraction	J	MG	—
Q9RXJ5	AlphaFold monomer V2.0 prediction for 50S ribosomal protein L16 (Q9RXJ5)	predicted	A	—	—

Ligands

MG · Magnesium ion · in 14 records
6NO · Avilamycin · in 2 records
6O1 · Evernimicin · in 2 records

Experiment against prediction

5DM6 chain J against the predicted model Q9RXJ5: TM-score 0.96, RMSD 0.85 Å
5DM6 chain J against the predicted model Q9RXJ5: TM-score 0.96, RMSD 0.85 Å
7A18 chain J against the predicted model Q9RXJ5: TM-score 0.96, RMSD 0.99 Å
7A18 chain J against the predicted model Q9RXJ5: TM-score 0.96, RMSD 0.99 Å
5DM7 chain J against the predicted model Q9RXJ5: TM-score 0.95, RMSD 0.96 Å
5DM7 chain J against the predicted model Q9RXJ5: TM-score 0.95, RMSD 0.96 Å
7A0R chain J against the predicted model Q9RXJ5: TM-score 0.95, RMSD 0.97 Å
7A0R chain J against the predicted model Q9RXJ5: TM-score 0.95, RMSD 0.97 Å
7A0S chain J against the predicted model Q9RXJ5: TM-score 0.95, RMSD 1.14 Å
7A0S chain J against the predicted model Q9RXJ5: TM-score 0.95, RMSD 1.14 Å

Elsewhere

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