UniProt Q9NZE8
39S ribosomal protein L35, mitochondrial (Q9NZE8)
39S ribosomal protein L35, mitochondrial (UniProt Q9NZE8): 79 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 172 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q9NZE8
- Protein
- 39S ribosomal protein L35, mitochondrial
- Experimental structures
- 79
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 172 · 55 records with a druggable one
Structures
80 records of Q9NZE8 in the MolNFT archive: 79 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3J7Y | Structure of the large ribosomal subunit from human mitochondria | electron microscopy | 3 | — | 2 (best 0.86) |
| 3J7Y | Structure of the large ribosomal subunit from human mitochondria | electron microscopy | 3 | — | — |
| 3J9M | Structure of the human mitochondrial ribosome (class 1) | electron microscopy | 3 | — | 4 (best 0.88) |
| 5OOL | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded… | electron microscopy | 3 | — | — |
| 5OOL | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded… | electron microscopy | 3 | — | — |
| 5OOM | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded… | electron microscopy | 3 | — | — |
| 5OOM | Structure of a native assembly intermediate of the human mitochondrial ribosome with unfolded… | electron microscopy | 3 | — | — |
| 6I9R | Large subunit of the human mitochondrial ribosome in complex with Virginiamycin M and Quinupristin | electron microscopy | 3 | — | — |
| 6NU2 | Structural insights into unique features of the human mitochondrial ribosome recycling | electron microscopy | 3 | — | — |
| 6NU3 | Structural insights into unique features of the human mitochondrial ribosome recycling | electron microscopy | 3 | — | 3 (best 0.87) |
| 6VLZ | Structure of the human mitochondrial ribosome-EF-G1 complex (ClassI) | electron microscopy | 3 | — | 1 (best 0.85) |
| 6VMI | Structure of the human mitochondrial ribosome-EF-G1 complex (ClassIII) | electron microscopy | 3 | — | 2 (best 0.86) |
| 6ZM5 | Human mitochondrial ribosome in complex with OXA1L, mRNA, A/A tRNA, P/P tRNA and nascent polypeptide | electron microscopy | 3 | K | 2 (best 0.88) |
| 6ZM6 | Human mitochondrial ribosome in complex with mRNA, A/A tRNA and P/P tRNA | electron microscopy | 3 | K | 3 (best 0.87) |
| 6ZS9 | Human mitochondrial ribosome in complex with ribosome recycling factor | electron microscopy | 3 | — | — |
| 6ZSA | Human mitochondrial ribosome bound to mRNA, A-site tRNA and P-site tRNA | electron microscopy | 3 | — | 2 (best 0.87) |
| 6ZSB | Human mitochondrial ribosome in complex with mRNA and P-site tRNA | electron microscopy | 3 | — | — |
| 6ZSC | Human mitochondrial ribosome in complex with E-site tRNA | electron microscopy | 3 | — | 1 (best 0.84) |
| 6ZSD | Human mitochondrial ribosome in complex with mRNA, P-site tRNA and E-site tRNA | electron microscopy | 3 | — | 1 (best 0.88) |
| 6ZSE | Human mitochondrial ribosome in complex with mRNA, A/P-tRNA and P/E-tRNA | electron microscopy | 3 | — | 1 (best 0.86) |
| 6ZSG | Human mitochondrial ribosome in complex with mRNA, A-site tRNA, P-site tRNA and E-site tRNA | electron microscopy | 3 | — | 1 (best 0.87) |
| 7A5F | Structure of the stalled human mitoribosome with P- and E-site mt-tRNAs | electron microscopy | 33 | — | 1 (best 0.86) |
| 7A5G | Structure of the elongating human mitoribosome bound to mtEF-Tu.GMPPCP and A/T mt-tRNA | electron microscopy | 33 | — | — |
| 7A5H | Structure of the split human mitoribosomal large subunit with rescue factors mtRF-R and MTRES1 | electron microscopy | 3 | — | 3 (best 0.84) |
| 7A5I | Structure of the human mitoribosome with A- P-and E-site mt-tRNAs | electron microscopy | 33 | — | — |
| 7A5J | Structure of the split human mitoribosomal large subunit with P-and E-site mt-tRNAs | electron microscopy | 3 | — | 3 (best 0.86) |
| 7A5K | Structure of the human mitoribosome in the post translocation state bound to mtEF-G1 | electron microscopy | 33 | — | 1 (best 0.86) |
| 7L08 | Cryo-EM structure of the human 55S mitoribosome-RRFmt complex. | electron microscopy | 3 | — | 3 (best 0.87) |
| 7L20 | Cryo-EM structure of the human 39S mitoribosomal subunit in complex with RRFmt and EF-G2mt. | electron microscopy | 3 | — | — |
| 7O9K | Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1, the… | electron microscopy | 3 | — | 4 (best 0.88) |
| 7O9M | Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1 and… | electron microscopy | 3 | — | 5 (best 0.86) |
| 7ODR | State A of the human mitoribosomal large subunit assembly intermediate | electron microscopy | 3 | MG | 4 (best 0.89) |
| 7ODS | State B of the human mitoribosomal large subunit assembly intermediate | electron microscopy | 3 | MG | 5 (best 0.88) |
| 7ODT | State C of the human mitoribosomal large subunit assembly intermediate | electron microscopy | 3 | — | 6 (best 0.86) |
| 7OF0 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | 3 | — | 3 (best 0.86) |
| 7OF0 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | 3 | — | — |
| 7OF2 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | 3 | GTP | 2 (best 0.86) |
| 7OF3 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | 3 | GTP | 5 (best 0.86) |
| 7OF4 | Structure of mature human mitochondrial ribosome large subunit in complex with GTPBP6 (PTC… | electron microscopy | 3 | — | — |
| 7OF5 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | 3 | GTP | 4 (best 0.88) |
| 7OF6 | Structure of mature human mitochondrial ribosome large subunit in complex with GTPBP6 (PTC… | electron microscopy | 3 | GTP | 3 (best 0.87) |
| 7OF7 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | 3 | — | 4 (best 0.83) |
| 7OG4 | Human mitochondrial ribosome in complex with P/E-tRNA | electron microscopy | 3 | — | 1 (best 0.87) |
| 7OI7 | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 2 | electron microscopy | 3 | — | 4 (best 0.90) |
| 7OI7 | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 2 | electron microscopy | 3 | — | — |
| 7OI8 | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3A | electron microscopy | 3 | — | 4 (best 0.89) |
| 7OI8 | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3A | electron microscopy | 3 | — | — |
| 7OI9 | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3B | electron microscopy | 3 | — | 5 (best 0.87) |
| 7OI9 | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3B | electron microscopy | 3 | — | — |
| 7OIA | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3C | electron microscopy | 3 | — | 6 (best 0.87) |
| 7OIA | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3C | electron microscopy | 3 | — | — |
| 7OIB | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3D | electron microscopy | 3 | — | 5 (best 0.87) |
| 7OIB | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 3D | electron microscopy | 3 | — | — |
| 7OIC | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 4 | electron microscopy | 3 | — | 4 (best 0.87) |
| 7OID | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 5A | electron microscopy | 3 | — | 4 (best 0.88) |
| 7OIE | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 5B | electron microscopy | 3 | — | 6 (best 0.86) |
| 7OIE | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 5B | electron microscopy | 3 | — | — |
| 7PD3 | Structure of the human mitoribosomal large subunit in complex with NSUN4.MTERF4.GTPBP7 and… | electron microscopy | 3 | — | — |
| 7PO4 | Assembly intermediate of human mitochondrial ribosome large subunit (largely unfolded rRNA with… | electron microscopy | 3 | — | 3 (best 0.86) |
| 7QH6 | Cryo-EM structure of the human mtLSU assembly intermediate upon MRM2 depletion - class 1 | electron microscopy | 3 | — | 5 (best 0.85) |
20 records more on the page itself.
Ligands
Experiment against prediction
- 6NU2 chain 3 against the predicted model Q9NZE8: TM-score 0.99, RMSD 0.42 Å
- 7OI8 chain 3 against the predicted model Q9NZE8: TM-score 0.98, RMSD 0.57 Å
- 7OI8 chain 3 against the predicted model Q9NZE8: TM-score 0.98, RMSD 0.57 Å
- 5OOL chain 3 against the predicted model Q9NZE8: TM-score 0.98, RMSD 0.59 Å
- 5OOL chain 3 against the predicted model Q9NZE8: TM-score 0.98, RMSD 0.59 Å
- 7L20 chain 3 against the predicted model Q9NZE8: TM-score 0.98, RMSD 0.58 Å
- 3J9M chain 3 against the predicted model Q9NZE8: TM-score 0.98, RMSD 0.59 Å
- 6NU3 chain 3 against the predicted model Q9NZE8: TM-score 0.97, RMSD 0.58 Å
- 7ODT chain 3 against the predicted model Q9NZE8: TM-score 0.97, RMSD 0.59 Å
- 7QH7 chain 3 against the predicted model Q9NZE8: TM-score 0.97, RMSD 0.59 Å
Elsewhere
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