UniProt Q9NXG6
Transmembrane prolyl 4-hydroxylase (Q9NXG6)
Transmembrane prolyl 4-hydroxylase (UniProt Q9NXG6), EC 1.14.11.29: 2 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q9NXG6
- Protein
- Transmembrane prolyl 4-hydroxylase
- EC
- 1.14.11.29
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 7
- Pockets
- 15 · 2 records with a druggable one
Structures
3 records of Q9NXG6 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6TP5 | Crystal structure of human Transmembrane prolyl 4-hydroxylase | x-ray diffraction | A, B | NAG, MAN, OGA, FE2, GLY, CA | 10 (best 0.78) |
| 6TP5 | Crystal structure of human transmembrane prolyl 4-hydroxylase | x-ray diffraction | A, B | NAG, MAN, OGA, FE2, CA, CL | — |
| Q9NXG6 | AlphaFold monomer V2.0 prediction for transmembrane prolyl 4-hydroxylase (Q9NXG6) | predicted | A | — | 5 (best 0.71) |
Ligands
Experiment against prediction
- 6TP5 chain B against the predicted model Q9NXG6: TM-score 1.00, RMSD 0.47 Å
- 6TP5 chain B against the predicted model Q9NXG6: TM-score 1.00, RMSD 0.47 Å
- 6TP5 chain A against the predicted model Q9NXG6: TM-score 0.99, RMSD 0.58 Å
- 6TP5 chain A against the predicted model Q9NXG6: TM-score 0.99, RMSD 0.58 Å
Elsewhere
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