UniProt Q9JI12
Vesicular glutamate transporter 2 (Q9JI12)
Vesicular glutamate transporter 2 (UniProt Q9JI12): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9JI12
- Protein
- Vesicular glutamate transporter 2
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 17 · 4 records with a druggable one
Structures
5 records of Q9JI12 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6V4D | Structure of the rat vesicular glutamate transporter 2 determined by single particle cryo-EM | electron microscopy | A | — | — |
| 7T3N | R184Q/E191Q mutant of rat vesicular glutamate transporter 2 (VGLUT2) | electron microscopy | A | C5B, I7Y | 3 (best 0.71) |
| 7T3O | Rat vesicular glutamate transporter 2 (VGLUT2) in low Cl condition | electron microscopy | A | — | 2 (best 0.74) |
| 8SBE | Structure of the rat vesicular glutamate transporter 2 determined by single-particle Cryo-EM | electron microscopy | A | — | 7 (best 0.75) |
| Q9JI12 | AlphaFold monomer V2.0 prediction for vesicular glutamate transporter 2 (Q9JI12) | predicted | A | — | 5 (best 0.69) |
Ligands
Experiment against prediction
- 8SBE chain A against the predicted model Q9JI12: TM-score 0.96, RMSD 1.52 Å
- 6V4D chain A against the predicted model Q9JI12: TM-score 0.96, RMSD 1.56 Å
- 7T3N chain A against the predicted model Q9JI12: TM-score 0.96, RMSD 2.03 Å
- 7T3O chain A against the predicted model Q9JI12: TM-score 0.95, RMSD 2.07 Å
Elsewhere
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