UniProt Q9I5W4
Metallopeptidase (Q9I5W4)
Metallopeptidase (UniProt Q9I5W4), EC 3.4.24.-: 8 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 51 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9I5W4
- Protein
- Metallopeptidase
- EC
- 3.4.24.-
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 51 · 3 records with a druggable one
Structures
9 records of Q9I5W4 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5KDV | IMPa metallopeptidase from Pseudomonas aeruginosa | x-ray diffraction | A | SO4, ZN | — |
| 5KDV | Impa metallopeptidase from pseudomonas aeruginosa | x-ray diffraction | A | SO4, ZN | — |
| 5KDW | IMPa metallopeptidase from Pseudomonas aeruginosa | x-ray diffraction | A, B | ZN, PO4 | 17 (best 0.65) |
| 5KDW | Impa metallopeptidase from pseudomonas aeruginosa | x-ray diffraction | A, B | ZN, PO4 | — |
| 5KDX | IMPa metallopeptidase in complex with T-antigen | x-ray diffraction | A, B | A2G, GAL, PO4, ZN, SER | 17 (best 0.65) |
| 5KDX | Impa metallopeptidase in complex with T-antigen | x-ray diffraction | A, B | A2G, GAL, PO4, ZN | — |
| 7JTV | Structure of IMPa from Pseudomonas aeruginosa in complex with an O-glycopeptide | x-ray diffraction | B, A | A2G, GAL, ZN | 17 (best 0.64) |
| 7JTV | Structure of impa from pseudomonas aeruginosa in complex with an O- glycopeptide | x-ray diffraction | B, A | A2G, GAL, ZN | — |
| Q9I5W4 | AlphaFold monomer V2.0 prediction for immunomodulating metalloprotease (Q9I5W4) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7JTV chain A against the predicted model Q9I5W4: TM-score 0.99, RMSD 0.99 Å
- 7JTV chain A against the predicted model Q9I5W4: TM-score 0.99, RMSD 0.99 Å
- 5KDV chain A against the predicted model Q9I5W4: TM-score 0.99, RMSD 0.74 Å
- 5KDV chain A against the predicted model Q9I5W4: TM-score 0.99, RMSD 0.74 Å
- 7JTV chain B against the predicted model Q9I5W4: TM-score 0.99, RMSD 1.23 Å
- 7JTV chain B against the predicted model Q9I5W4: TM-score 0.99, RMSD 1.23 Å
- 5KDW chain B against the predicted model Q9I5W4: TM-score 0.98, RMSD 1.27 Å
- 5KDW chain A against the predicted model Q9I5W4: TM-score 0.98, RMSD 1.30 Å
- 5KDW chain A against the predicted model Q9I5W4: TM-score 0.98, RMSD 1.30 Å
- 5KDX chain B against the predicted model Q9I5W4: TM-score 0.98, RMSD 1.41 Å
Elsewhere
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