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UniProt Q9HV55

Translation initiation factor IF-2 (Q9HV55)

Translation initiation factor IF-2 (UniProt Q9HV55): 7 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 7 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
Q9HV55
Protein
Translation initiation factor IF-2
Experimental structures
7
Predicted models
1
Ligands
4
Pockets
7 · 1 record with a druggable one

Structures

8 records of Q9HV55 in the MolNFT archive: 7 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
7UIUN2 sub-domain of IF2 bound to the 30S subunit in the Pseudomonas aeruginosa 70S ribosome initiation…electron microscopyx——
7UIUN2 sub-domain of IF2 bound to the 30S subunit in the pseudomonas aeruginosa 70S ribosome initiation…electron microscopyx——
7UNQCompact IF2-GDP bound to the pseudomonas aeruginosa 70S ribosome initiation complex, from focused…electron microscopyxGDP—
7UNRPseudomonas aeruginosa 70S ribosome initiation complex bound to compact IF2-GDP (composite…electron microscopyxGDP—
7UNTCompact IF2-GDP bound to the Pseudomonas aeruginosa 70S ribosome initiation complex, from focused…electron microscopyxGDP7 (best 0.64)
7UNTCompact IF2-GDP bound to the pseudomonas aeruginosa 70S ribosome initiation complex, from focused…electron microscopyxGDP—
7UNVPseudomonas aeruginosa 70S ribosome initiation complex bound to IF2-GDPCP (structure II-A)electron microscopyxFME, MG, GCP—
Q9HV55AlphaFold monomer V2.0 prediction for translation initiation factor if-2 (Q9HV55)predictedA——

Ligands

  • GDP · Guanosine-5'-diphosphate · in 4 records
  • FME · N-formylmethionine · in 1 record
  • GCP · Phosphomethylphosphonic acid guanylate ester · in 1 record
  • MG · Magnesium ion · in 1 record

Experiment against prediction

Elsewhere

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