MolNFT v1 · #188929 · protein
Compact IF2-GDP bound to the pseudomonas aeruginosa 70S ribosome initiation complex, from focused classification and refinement (I-a)
7UNQ · Translation initiation factor if-2: “Compact IF2-GDP bound to the pseudomonas aeruginosa 70S ribosome initiation complex, from focused…”. Electron microscopy, 1 ligand (GDP), 7 pockets (best druggability 0.54). MolNFT v1 #188929 on…
- PDB
- 7UNQ
- Type
- protein
- Length
- 486 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Translation initiation factor if-2
- UniProt
- Q9HV55
- Ligands
- GDP
- Pockets
- 7 · best druggability 0.54
Structure
electron microscopy · 1 distinct chain · 24% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| x | Translation initiation factor if-2 | protein | 486 | 24% helix, 30% strand | Q9HV55 |
Ligands and binding sites
- GDP · Guanosine-5'-diphosphate · ligand · chains x
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 257 | 0.54 | 0.77 | 32 | empty |
| 2 | 99 | 0.46 | 0.80 | 24 | empty |
| 3 | 151 | 0.42 | 0.75 | 20 | empty |
| 4 | 69 | 0.40 | 0.80 | 18 | empty |
| 5 | 79 | 0.39 | 0.78 | 22 | empty |
Compared structures
- 7UNQ · Compact IF2-GDP bound to the Pseudomonas aeruginosa 70S ribosome initiation complex, from… · the same entry in another collection · chain x against x, TM-score 1.00
- Q9HV55 · AlphaFold monomer V2.0 prediction for translation initiation factor if-2 (Q9HV55) · a predicted model of the same protein · chain x against A, TM-score 0.57
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HV55
- Elsewhere: RCSB PDB 7UNQ · PDBe 7UNQ · UniProt Q9HV55
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