MolNFT v1 · #188930 · protein
Compact IF2-GDP bound to the pseudomonas aeruginosa 70S ribosome initiation complex, from focused classification and refinement (I-B)
7UNT · Translation initiation factor if-2: “Compact IF2-GDP bound to the pseudomonas aeruginosa 70S ribosome initiation complex, from focused…”. Electron microscopy, 1 ligand (GDP), 7 pockets (best druggability 0.64). MolNFT v1 #188930 on…
- PDB
- 7UNT
- Type
- protein
- Length
- 472 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Translation initiation factor if-2
- UniProt
- Q9HV55
- Ligands
- GDP
- Pockets
- 7 · best druggability 0.64
Structure
electron microscopy · 1 distinct chain · 26% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| x | Translation initiation factor if-2 | protein | 472 | 26% helix, 28% strand | Q9HV55 |
Ligands and binding sites
- GDP · Guanosine-5'-diphosphate · ligand · chains x
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 87 | 0.64 | 0.91 | 35 | empty |
| 2 | 323 | 0.61 | 0.78 | 40 | empty |
| 3 | 123 | 0.46 | 0.78 | 26 | empty |
| 4 | 50 | 0.39 | 0.82 | 19 | empty |
| 5 | 109 | 0.39 | 0.75 | 21 | empty |
Compared structures
- 7UNT · Compact IF2-GDP bound to the Pseudomonas aeruginosa 70S ribosome initiation complex, from… · the same entry in another collection · chain x against x, TM-score 1.00
- Q9HV55 · AlphaFold monomer V2.0 prediction for translation initiation factor if-2 (Q9HV55) · a predicted model of the same protein · chain x against A, TM-score 0.55
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9HV55
- Elsewhere: RCSB PDB 7UNT · PDBe 7UNT · UniProt Q9HV55
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