UniProt Q9H816
5' exonuclease Apollo (Q9H816)
5' exonuclease Apollo (UniProt Q9H816), EC 3.1.-.-: 10 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9H816
- Protein
- 5' exonuclease Apollo
- EC
- 3.1.-.-
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 11 · 1 record with a druggable one
Structures
11 records of Q9H816 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3BUA | Crystal Structure of TRF2 TRFH domain and APOLLO peptide complex | x-ray diffraction | E, F, G, H | — | — |
| 3BUA | Crystal structure of TRF2 trfh domain and apollo peptide complex | x-ray diffraction | E, F, G, H | — | — |
| 5AHO | Crystal structure of human 5' exonuclease Apollo | x-ray diffraction | A | — | — |
| 5AHO | Crystal structure of human 5' exonuclease apollo | x-ray diffraction | A | — | — |
| 7A1F | Crystal structure of human 5' exonuclease Appollo in complex with 5'dAMP | x-ray diffraction | A, L | FE, NI, D5M | 6 (best 0.77) |
| 7A1F | Crystal structure of human 5' exonuclease appollo in complex with 5'DAMP | x-ray diffraction | A, L | FE, NI, D5M | — |
| 7B2X | Crystal structure of human 5' exonuclease Appollo H61Y variant | x-ray diffraction | A | NI | 3 (best 0.49) |
| 7B2X | Crystal structure of human 5' exonuclease appollo H61Y variant | x-ray diffraction | A | NI | — |
| 7B9B | Crystal structure of human 5' exonuclease Appollo APO form | x-ray diffraction | A | NI | 2 (best 0.48) |
| 7B9B | Crystal structure of human 5' exonuclease appollo apo form | x-ray diffraction | A | NI | — |
| Q9H816 | AlphaFold monomer V2.0 prediction for 5' exonuclease apollo (Q9H816) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7A1F chain A against the predicted model Q9H816: TM-score 1.00, RMSD 0.38 Å
- 7A1F chain A against the predicted model Q9H816: TM-score 1.00, RMSD 0.38 Å
- 7A1F chain L against the predicted model Q9H816: TM-score 0.99, RMSD 0.59 Å
- 7A1F chain L against the predicted model Q9H816: TM-score 0.99, RMSD 0.59 Å
- 5AHO chain A against the predicted model Q9H816: TM-score 0.98, RMSD 0.84 Å
- 5AHO chain A against the predicted model Q9H816: TM-score 0.98, RMSD 0.84 Å
- 7B9B chain A against the predicted model Q9H816: TM-score 0.95, RMSD 1.65 Å
- 7B9B chain A against the predicted model Q9H816: TM-score 0.95, RMSD 1.65 Å
- 7B2X chain A against the predicted model Q9H816: TM-score 0.94, RMSD 1.66 Å
- 7B2X chain A against the predicted model Q9H816: TM-score 0.94, RMSD 1.66 Å
Elsewhere
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