UniProt Q9GZU7
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (Q9GZU7)
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (UniProt Q9GZU7), EC 3.1.3.16: 22 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 6 pockets. Binding sites, druggability and…
- UniProt
- Q9GZU7
- Protein
- Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
- EC
- 3.1.3.16
- Experimental structures
- 22
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 6 · 0 records with a druggable one
Structures
23 records of Q9GZU7 in the MolNFT archive: 22 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1T9Z | Three-dimensional structure of a RNA-polymerase II binding protein. | x-ray diffraction | A | MG | 1 (best 0.30) |
| 1T9Z | Three-dimensional structure of a RNA-polymerase II binding protein. | x-ray diffraction | A | — | — |
| 1TA0 | Three-dimensional structure of a RNA-polymerase II binding protein with associated ligand. | x-ray diffraction | A | MG | 1 (best 0.30) |
| 1TA0 | Three-dimensional structure of a RNA-polymerase II binding protein with associated ligand. | x-ray diffraction | A | — | — |
| 2GHQ | CTD-specific phosphatase Scp1 in complex with peptide C-terminal domain of RNA polymerase II | x-ray diffraction | A, B | MG | 1 (best 0.33) |
| 2GHQ | Ctd-specific phosphatase SCP1 in complex with peptide C-terminal domain of RNA polymerase II | x-ray diffraction | A, B | — | — |
| 2GHT | CTD-specific phosphatase Scp1 in complex with peptide from C-terminal domain of RNA polymerase II | x-ray diffraction | A, B | MG | — |
| 2GHT | Ctd-specific phosphatase SCP1 in complex with peptide from C-terminal domain of RNA polymerase II | x-ray diffraction | A, B | — | — |
| 3L0B | Crystal structure of SCP1 phosphatase D206A mutant phosphoryl-intermediate | x-ray diffraction | A, B | — | — |
| 3L0B | Crystal structure of SCP1 phosphatase D206A mutant phosphoryl- intermediate | x-ray diffraction | A, B | — | — |
| 3L0C | Crystal structure of SCP1 phosphatase D206A mutant with trapped inorganic phosphate | x-ray diffraction | A, B | — | — |
| 3L0C | Crystal structure of SCP1 phosphatase D206A mutant with trapped inorganic phosphate | x-ray diffraction | A, B | — | — |
| 3L0Y | Crystal structure OF SCP1 phosphatase D98A mutant | x-ray diffraction | A, B | — | — |
| 3L0Y | Crystal structure of SCP1 phosphatase D98A mutant | x-ray diffraction | A, B | — | — |
| 3PGL | Crystal structure of human small C-terminal domain phosphatase 1 (Scp1) bound to rabeprazole | x-ray diffraction | A, B | — | — |
| 3PGL | Crystal structure of human small C-terminal domain phosphatase 1 (SCP1) bound to rabeprazole | x-ray diffraction | A, B | — | — |
| 4YGY | Crystal Structure of Human Scp1 bound to trans-proline peptidomimetic CTD phospho-Ser5 peptide | x-ray diffraction | A, B | — | — |
| 4YGY | Crystal structure of human SCP1 bound to trans-proline peptidomimetic ctd phospho-SER5 peptide | x-ray diffraction | A, B | — | — |
| 4YH1 | Structure of Human Scp1 bound to cis-proline peptidomimetic CTD phospho-Ser5 peptide | x-ray diffraction | A, B | — | — |
| 4YH1 | Structure of human SCP1 bound to cis-proline peptidomimetic ctd phospho-SER5 peptide | x-ray diffraction | A, B | — | — |
| 6DU3 | Structure of Scp1 D96N bound to REST-pS861/4 peptide | x-ray diffraction | A, B | MG | 3 (best 0.38) |
| 6DU3 | Structure of SCP1 D96N bound to rest-PS861/4 peptide | x-ray diffraction | A, B | MG | — |
| Q9GZU7 | AlphaFold monomer V2.0 prediction for carboxy-terminal domain RNA polymerase II polypeptide a small… | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 6 records
Experiment against prediction
- 4YH1 chain B against the predicted model Q9GZU7: TM-score 1.00, RMSD 0.30 Å
- 4YH1 chain B against the predicted model Q9GZU7: TM-score 1.00, RMSD 0.30 Å
- 4YGY chain B against the predicted model Q9GZU7: TM-score 1.00, RMSD 0.30 Å
- 4YGY chain B against the predicted model Q9GZU7: TM-score 1.00, RMSD 0.30 Å
- 3L0C chain A against the predicted model Q9GZU7: TM-score 1.00, RMSD 0.31 Å
- 3L0C chain A against the predicted model Q9GZU7: TM-score 1.00, RMSD 0.31 Å
- 3L0Y chain A against the predicted model Q9GZU7: TM-score 1.00, RMSD 0.31 Å
- 3L0Y chain A against the predicted model Q9GZU7: TM-score 1.00, RMSD 0.31 Å
- 4YH1 chain A against the predicted model Q9GZU7: TM-score 0.99, RMSD 0.38 Å
- 4YH1 chain A against the predicted model Q9GZU7: TM-score 0.99, RMSD 0.38 Å
Elsewhere
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