MolNFT v1 · #69789 · protein
Crystal structure of SCP1 phosphatase D98A mutant
3L0Y · Carboxy-terminal domain RNA polymerase II polypeptide a…: “Crystal structure of SCP1 phosphatase D98A mutant”. X-ray diffraction, 1 ligand (MG), 3 pockets (best druggability 0.53). MolNFT v1 #69789 on GenesisL1: 3D structure…
- PDB
- 3L0Y
- Type
- protein
- Length
- 358 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Carboxy-terminal domain RNA polymerase II polypeptide a small phosphatase 1
- EC
- 3.1.3.16
- UniProt
- Q9GZU7
- Ligands
- MG
- Pockets
- 3 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 31% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Carboxy-terminal domain RNA polymerase II polypeptide a small phosphatase 1 (EC 3.1.3.16) | protein | 179 | 31% helix, 27% strand | Q9GZU7 |
Ligands and binding sites
- MG · Magnesium ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 282 | 0.53 | 0.75 | 41 | empty |
| 2 | 148 | 0.48 | 0.77 | 30 | MG |
| 3 | 133 | 0.43 | 0.76 | 27 | MG |
Interfaces
1 interface between chains.
- A–B · 386 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9GZU7
- Elsewhere: RCSB PDB 3L0Y · PDBe 3L0Y · UniProt Q9GZU7
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