MolNFT v1 · #22601 · protein
Three-dimensional structure of a RNA-polymerase II binding protein.
1T9Z · Carboxy-terminal domain RNA polymerase II polypeptide a…: “Three-dimensional structure of a RNA-polymerase II binding protein.”. X-ray diffraction, 1 ligand (MG), 1 pocket (best druggability 0.30). MolNFT v1 #22601 on GenesisL1: 3D…
- PDB
- 1T9Z
- Type
- protein
- Length
- 181 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Carboxy-terminal domain RNA polymerase II polypeptide a small phosphatase 1
- EC
- 3.1.3.16
- UniProt
- Q9GZU7
- Ligands
- MG
- Pockets
- 1 · best druggability 0.30
Structure
x-ray diffraction · 1 distinct chain · 32% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Carboxy-terminal domain RNA polymerase II polypeptide a small phosphatase 1 (EC 3.1.3.16) | protein | 181 | 32% helix, 25% strand | Q9GZU7 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 68 | 0.30 | 0.74 | 13 | CIT |
Modifications
Observed in the structure: 5 modified (engineered).
Compared structures
- 1T9Z · Three-dimensional structure of a RNA-polymerase II binding protein. · the same entry in another collection · chain A against A, TM-score 1.00
- Q9GZU7 · AlphaFold monomer V2.0 prediction for carboxy-terminal domain RNA polymerase II… · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9GZU7
- Elsewhere: RCSB PDB 1T9Z · PDBe 1T9Z · UniProt Q9GZU7
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