UniProt Q9EZJ8
sigma factor SigA (Q9EZJ8)
sigma factor SigA (UniProt Q9EZJ8): 33 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 33 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9EZJ8
- Protein
- sigma factor SigA
- Experimental structures
- 33
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 33 · 7 records with a druggable one
Structures
34 records of Q9EZJ8 in the MolNFT archive: 33 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1KU2 | Crystal Structure of Thermus aquaticus RNA Polymerase Sigma Subunit Fragment Containing Regions 1.2… | x-ray diffraction | A, B | SO4 | 7 (best 0.77) |
| 1KU2 | Crystal structure of thermus aquaticus RNA polymerase sigma subunit fragment containing regions 1.2… | x-ray diffraction | A, B | — | — |
| 1KU3 | Crystal Structure of Thermus aquaticus RNA Polymerase Sigma Subunit Fragment, Region 4 | x-ray diffraction | A | — | — |
| 1KU3 | Crystal structure of thermus aquaticus RNA polymerase sigma subunit fragment, region 4 | x-ray diffraction | A | — | — |
| 1KU7 | Crystal Structure of Thermus aquatics RNA Polymerase SigmaA Subunit Region 4 Bound to-35 Element DNA | x-ray diffraction | A, D | — | — |
| 1KU7 | Crystal structure of thermus aquatics RNA polymerase sigmaa subunit region 4 bound to-35 element DNA | x-ray diffraction | A, D | — | — |
| 1L9U | Thermus aquaticus RNA polymerase holoenzyme at 4 a resolution | x-ray diffraction | H, Q | — | 1 (best 0.56) |
| 1L9U | Thermus aquaticus RNA polymerase holoenzyme at 4 a resolution | x-ray diffraction | H, Q | — | — |
| 1L9Z | Thermus aquaticus RNA Polymerase Holoenzyme/Fork-Junction Promoter DNA Complex at 6.5 A Resolution | x-ray diffraction | H | — | 3 (best 0.59) |
| 1L9Z | Thermus aquaticus RNA polymerase HOLOENZYME/FORK-junction promoter DNA complex at 6.5 a resolution | x-ray diffraction | H | — | — |
| 1RIO | Structure of bacteriophage lambda cI-NTD in complex with sigma-region4 of Thermus aquaticus bound… | x-ray diffraction | H | — | 1 (best 0.58) |
| 1RIO | Structure of bacteriophage lambda ci-ntd in complex with sigma-REGION4 of thermus aquaticus bound… | x-ray diffraction | H | — | — |
| 3LES | 2F5 Epitope scaffold ES2 | x-ray diffraction | A, B | — | — |
| 3LES | 2F5 epitope scaffold ES2 | x-ray diffraction | A, B | — | — |
| 3LEV | HIV-1 antibody 2F5 in complex with epitope scaffold ES2 | x-ray diffraction | A | — | — |
| 3LEV | HIV-1 antibody 2F5 in complex with epitope scaffold ES2 | x-ray diffraction | A | — | — |
| 3N97 | RNA polymerase alpha C-terminal domain (E. coli) and sigma region 4 (T. aq. mutant) bound to… | x-ray diffraction | A, D | — | — |
| 3N97 | RNA polymerase alpha C-terminal domain (E. COLI) and sigma region 4 (T. aq. mutant) bound to… | x-ray diffraction | A, D | — | — |
| 3UGO | Crystal structure of RNA-polymerase sigma subunit domain 2 complexed with -10 promoter element… | x-ray diffraction | A | — | — |
| 3UGO | Crystal structure of RNA-polymerase sigma subunit domain 2 complexed with -10 promoter element… | x-ray diffraction | A | — | — |
| 3UGP | Crystal structure of RNA-polymerase sigma subunit domain 2 complexed with -10 promoter element… | x-ray diffraction | A | — | — |
| 3UGP | Crystal structure of RNA-polymerase sigma subunit domain 2 complexed with -10 promoter element… | x-ray diffraction | A | — | — |
| 4KI2 | Crystallographic analysis of an RNA-polymerase sigma-subunit fragment complexed with -10 promoter… | x-ray diffraction | A, B | — | — |
| 4KI2 | Crystallographic analysis of an RNA-polymerase sigma-subunit fragment complexed with -10 promoter… | x-ray diffraction | A, B | — | — |
| 4XLN | Crystal structure of T. aquaticus transcription initiation complex containing bubble promoter and… | x-ray diffraction | F, L | — | 10 (best 0.87) |
| 4XLN | Crystal structure of T. aquaticus transcription initiation complex containing bubble promoter and… | x-ray diffraction | F, L | — | — |
| 4XLP | Crystal structure of T.AQUATICUS transcription initiation complex containing upstream fork promoter | x-ray diffraction | F, L | — | — |
| 4XLQ | Crystal structure of T.aquaticus transcription initiation complex containing upstream fork (-11… | x-ray diffraction | F, L | — | — |
| 4XLQ | Crystal structure of T.AQUATICUS transcription initiation complex containing upstream fork (-11… | x-ray diffraction | F, L | — | — |
| 4XLR | Crystal structure of T.AQUATICUS transcription initiation complex with card containing bubble… | x-ray diffraction | F, L | — | — |
| 4XLS | Crystal structure of T. aquaticus transcription initiation complex with CarD containing upstream… | x-ray diffraction | F, L | — | 7 (best 0.83) |
| 4XLS | Crystal structure of T. aquaticus transcription initiation complex with card containing upstream… | x-ray diffraction | F, L | — | — |
| 5TJG | Thermus aquaticus DELTA1.1-sigmaa HOLOENZYME/DOWNSTREAM-fork promoter complex with an open clamp | x-ray diffraction | F | — | — |
| Q9EZJ8 | AlphaFold monomer V2.0 prediction for RNA polymerase sigma factor siga (Q9EZJ8) | predicted | A | — | 4 (best 0.71) |
Ligands
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 3N97 chain D against the predicted model Q9EZJ8: TM-score 0.96, RMSD 0.52 Å
- 3N97 chain D against the predicted model Q9EZJ8: TM-score 0.96, RMSD 0.52 Å
- 3N97 chain A against the predicted model Q9EZJ8: TM-score 0.95, RMSD 0.65 Å
- 3N97 chain A against the predicted model Q9EZJ8: TM-score 0.95, RMSD 0.65 Å
- 4XLP chain F against the predicted model Q9EZJ8: TM-score 0.94, RMSD 1.79 Å
- 1RIO chain H against the predicted model Q9EZJ8: TM-score 0.94, RMSD 0.67 Å
- 1RIO chain H against the predicted model Q9EZJ8: TM-score 0.94, RMSD 0.67 Å
- 4XLN chain L against the predicted model Q9EZJ8: TM-score 0.94, RMSD 1.91 Å
- 4XLN chain F against the predicted model Q9EZJ8: TM-score 0.94, RMSD 1.87 Å
- 4XLN chain F against the predicted model Q9EZJ8: TM-score 0.94, RMSD 1.87 Å
Elsewhere
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