MolNFT v1 · #428781 · protein
AlphaFold monomer V2.0 prediction for RNA polymerase sigma factor siga (Q9EZJ8)
Q9EZJ8: “AlphaFold monomer V2.0 prediction for RNA polymerase sigma factor siga (Q9EZJ8)”. 4 pockets (best druggability 0.71). MolNFT v1 #428781 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- Accession
- Q9EZJ8
- Type
- protein
- Length
- 438 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x86CC08B8660Fa01B25046dEAd64f4F553fa9FA76
- Molecule
- RNA polymerase sigma factor siga
- UniProt
- Q9EZJ8
- Pockets
- 4 · best druggability 0.71
Structure
1 distinct chain · 55% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | RNA polymerase sigma factor siga | protein | 438 | 55% helix, 0% strand | Q9EZJ8 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 738 | 0.71 | 0.78 | 62 | empty |
| 2 | 140 | 0.49 | 0.78 | 14 | empty |
| 3 | 170 | 0.48 | 0.76 | 25 | empty |
| 4 | 89 | 0.36 | 0.74 | 18 | empty |
Compared structures
- 4XLN · Crystal structure of T. aquaticus transcription initiation complex containing bubble… · an experimental structure of the same protein · chain A against L, TM-score 0.75
- 4XLP · Crystal structure of T.AQUATICUS transcription initiation complex containing upstream… · an experimental structure of the same protein · chain A against F, TM-score 0.75
- 4XLN · Crystal structure of T. aquaticus transcription initiation complex containing bubble… · an experimental structure of the same protein · chain A against F, TM-score 0.75
- 4XLS · Crystal structure of T. aquaticus transcription initiation complex with CarD containing… · an experimental structure of the same protein · chain A against L, TM-score 0.75
- 4XLQ · Crystal structure of T.aquaticus transcription initiation complex containing upstream… · an experimental structure of the same protein · chain A against F, TM-score 0.74
- 4XLQ · Crystal structure of T.AQUATICUS transcription initiation complex containing upstream… · an experimental structure of the same protein · chain A against F, TM-score 0.74
- 4XLS · Crystal structure of T. aquaticus transcription initiation complex with card containing… · an experimental structure of the same protein · chain A against F, TM-score 0.74
- 4XLR · Crystal structure of T.AQUATICUS transcription initiation complex with card containing… · an experimental structure of the same protein · chain A against F, TM-score 0.74
- 5TJG · Thermus aquaticus DELTA1.1-sigmaa HOLOENZYME/DOWNSTREAM-fork promoter complex with an… · an experimental structure of the same protein · chain A against F, TM-score 0.72
- 1L9Z · Thermus aquaticus RNA polymerase HOLOENZYME/FORK-junction promoter DNA complex at 6.5 a… · an experimental structure of the same protein · chain A against H, TM-score 0.66
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9EZJ8
- Elsewhere: UniProt Q9EZJ8 · AlphaFold DB Q9EZJ8
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