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AlphaFold monomer V2.0 prediction for RNA polymerase sigma factor siga (Q9EZJ8)

Analyse AlphaFold monomer V2.0 prediction for RNA polymerase sigma factor siga (Q9EZJ8) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q9EZJ8
Type
protein
Length
438 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x86CC08B8660Fa01B25046dEAd64f4F553fa9FA76
Molecule
RNA polymerase sigma factor siga
UniProt
Q9EZJ8
Pockets
4 · best druggability 0.71

Structure

1 distinct chain · 55% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARNA polymerase sigma factor sigaprotein43855% helix, 0% strandQ9EZJ8

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
17380.710.7862empty
21400.490.7814empty
31700.480.7625empty
4890.360.7418empty

Compared structures

  • 4XLN · Crystal structure of T. aquaticus transcription initiation complex containing bubble… · an experimental structure of the same protein · chain A against L, TM-score 0.75
  • 4XLP · Crystal structure of T.AQUATICUS transcription initiation complex containing upstream… · an experimental structure of the same protein · chain A against F, TM-score 0.75
  • 4XLN · Crystal structure of T. aquaticus transcription initiation complex containing bubble… · an experimental structure of the same protein · chain A against F, TM-score 0.75
  • 4XLS · Crystal structure of T. aquaticus transcription initiation complex with CarD containing… · an experimental structure of the same protein · chain A against L, TM-score 0.75
  • 4XLQ · Crystal structure of T.aquaticus transcription initiation complex containing upstream… · an experimental structure of the same protein · chain A against F, TM-score 0.74
  • 4XLQ · Crystal structure of T.AQUATICUS transcription initiation complex containing upstream… · an experimental structure of the same protein · chain A against F, TM-score 0.74
  • 4XLS · Crystal structure of T. aquaticus transcription initiation complex with card containing… · an experimental structure of the same protein · chain A against F, TM-score 0.74
  • 4XLR · Crystal structure of T.AQUATICUS transcription initiation complex with card containing… · an experimental structure of the same protein · chain A against F, TM-score 0.74
  • 5TJG · Thermus aquaticus DELTA1.1-sigmaa HOLOENZYME/DOWNSTREAM-fork promoter complex with an… · an experimental structure of the same protein · chain A against F, TM-score 0.72
  • 1L9Z · Thermus aquaticus RNA polymerase HOLOENZYME/FORK-junction promoter DNA complex at 6.5 a… · an experimental structure of the same protein · chain A against H, TM-score 0.66

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