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UniProt Q9CPU2

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (Q9CPU2)

NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (UniProt Q9CPU2): 14 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 10 pockets. Binding sites, druggability and experiment…

UniProt
Q9CPU2
Protein
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial
Experimental structures
14
Predicted models
1
Ligands
2
Pockets
10 · 6 records with a druggable one

Structures

15 records of Q9CPU2 in the MolNFT archive: 14 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
6G2JMouse mitochondrial complex I in the active stateelectron microscopyj—1 (best 0.80)
6G2JMouse mitochondrial complex I in the active stateelectron microscopyj——
6G72Mouse mitochondrial complex I in the deactive stateelectron microscopyj——
6ZR2Cryo-EM structure of respiratory complex I in the active state from mus musculus at 3.1 aelectron microscopyj——
6ZTQCryo-EM structure of respiratory complex I from mus musculus inhibited by piericidin a at 3.0 aelectron microscopyj——
7AK5Cryo-EM structure of respiratory complex I in the deactive state from Mus musculus at 3.2 Aelectron microscopyj——
7AK5Cryo-EM structure of respiratory complex I in the deactive state from mus musculus at 3.2 aelectron microscopyj——
7AK6Cryo-EM structure of ND6-P25L mutant respiratory complex I from mus musculus at 3.8 aelectron microscopyj——
7B93Cryo-EM structure of mitochondrial complex I from mus musculus inhibited by iacs-2858 at 3.0 aelectron microscopyj——
8IAQRespiratory complex Membrane domain of CI, focused map of type I, Wild type mouse under…electron microscopyjPC12 (best 0.87)
8IBDRespiratory complex CI:CIII2, type II, Wild type mouse under cold temperatureelectron microscopyj3PE2 (best 0.86)
8IC4Respiratory complex Membrane domain of CI, focus-refined of type I, PERK -/- mouse under cold…electron microscopyj3PE2 (best 0.87)
8PW6C respirasome from murine liverelectron microscopyj1—1 (best 0.84)
8RGRClosed Complex I from murine liverelectron microscopyj—2 (best 0.82)
Q9CPU2AlphaFold monomer V2.0 prediction for NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2…predictedA——

Ligands

  • 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · in 2 records
  • PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · in 1 record

Experiment against prediction

Elsewhere

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