UniProt Q9BXC1
Probable G-protein coupled receptor 174 (Q9BXC1)
Probable G-protein coupled receptor 174 (UniProt Q9BXC1): 3 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q9BXC1
- Protein
- Probable G-protein coupled receptor 174
- Experimental structures
- 3
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 18 · 4 records with a druggable one
Structures
4 records of Q9BXC1 in the MolNFT archive: 3 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7XV3 | Cryo-EM structure of LPS-bound GPR174 in complex with Gs protein | electron microscopy | R | WJS | 6 (best 0.78) |
| 8IZB | Lysophosphatidylserine receptor GPR174-Gs complex | electron microscopy | R | UBL, SER, CLR | 4 (best 0.77) |
| 8KH5 | Cryo-EM structure of the GPR174-Gs complex bound to endogenous lysoPS | electron microscopy | A | CLR, LPS | 5 (best 0.76) |
| Q9BXC1 | AlphaFold monomer V2.0 prediction for probable G-protein coupled receptor 174 (Q9BXC1) | predicted | A | — | 3 (best 0.74) |
Ligands
- CLR · Cholesterol · in 2 records
- LPS · O-{hydroxy[((2r)-2-hydroxy-3-{[(1S)-1-hydroxypentadecyl]oxy}propyl)oxy]phosphoryl}-L-serine · in 1 record
- SER · Serine · in 1 record
- UBL · [(2R)-2-oxidanyl-3-phosphonooxy-propyl] (Z)-octadec-9-enoate · in 1 record
- WJS · (2~{S})-2-$l^{4}-azanyl-3-[[(2~{R})-3-octadecanoyloxy-2-oxidanyl-propoxy]-oxidanyl-oxidanylidene-$l^{6}-phosphanyl]oxy-propanoic acid · in 1 record
Experiment against prediction
- 8KH5 chain A against the predicted model Q9BXC1: TM-score 0.93, RMSD 1.87 Å
- 8IZB chain R against the predicted model Q9BXC1: TM-score 0.93, RMSD 1.95 Å
- 7XV3 chain R against the predicted model Q9BXC1: TM-score 0.90, RMSD 2.42 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.