UniProt Q99181
Protein HSH49 (Q99181)
Protein HSH49 (UniProt Q99181): 12 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q99181
- Protein
- Protein HSH49
- Experimental structures
- 12
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
13 records of Q99181 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5GM6 | Cryo-EM structure of the activated spliceosome (Bact complex) at 3.5 angstrom resolution | electron microscopy | e | — | — |
| 5LSB | Crystal structure of yeast Hsh49p in complex with Cus1p binding domain. | x-ray diffraction | A, C, F | — | — |
| 5LSB | Crystal structure of yeast HSH49P in complex with CUS1P binding domain. | x-ray diffraction | A, C, F | — | — |
| 5LSL | Crystal structure of yeast Hsh49p in complex with Cus1p binding domain. | x-ray diffraction | A, B, C, D | — | — |
| 5LSL | Crystal structure of yeast HSH49P in complex with CUS1P binding domain. | x-ray diffraction | A, B, C, D | — | — |
| 5NRL | Structure of a pre-catalytic spliceosome | electron microscopy | R | — | — |
| 5ZWO | Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom | electron microscopy | 4 | — | — |
| 5ZWO | Cryo-EM structure of the yeast B complex at average resolution of 3.9 ångström | electron microscopy | 4 | — | — |
| 6G90 | Prespliceosome structure provides insight into spliceosome assembly and regulation (map A2) | electron microscopy | R | — | 1 (best 0.80) |
| 6G90 | Prespliceosome structure provides insight into spliceosome assembly and regulation (MAP A2) | electron microscopy | R | — | — |
| 7OQB | The U2 part of saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) | electron microscopy | R | — | — |
| 7OQE | Saccharomyces cerevisiae spliceosomal pre-a complex (delta bs-a ACT1) | electron microscopy | R | — | — |
| Q99181 | AlphaFold monomer V2.0 prediction for protein HSH49 (Q99181) | predicted | A | — | — |
Experiment against prediction
- 5LSL chain A against the predicted model Q99181: TM-score 0.99, RMSD 0.34 Å
- 5LSL chain A against the predicted model Q99181: TM-score 0.99, RMSD 0.34 Å
- 5LSB chain F against the predicted model Q99181: TM-score 0.82, RMSD 2.69 Å
- 5LSB chain F against the predicted model Q99181: TM-score 0.82, RMSD 2.69 Å
- 5LSB chain A against the predicted model Q99181: TM-score 0.82, RMSD 2.75 Å
- 5LSB chain A against the predicted model Q99181: TM-score 0.82, RMSD 2.75 Å
- 7OQB chain R against the predicted model Q99181: TM-score 0.55, RMSD 2.68 Å
- 6G90 chain R against the predicted model Q99181: TM-score 0.55, RMSD 2.68 Å
- 6G90 chain R against the predicted model Q99181: TM-score 0.55, RMSD 2.68 Å
- 7OQE chain R against the predicted model Q99181: TM-score 0.55, RMSD 2.68 Å
Elsewhere
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