UniProt Q96SD1
Protein artemis (Q96SD1)
Protein artemis (UniProt Q96SD1), EC 3.1.-.-: 25 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 34 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q96SD1
- Protein
- Protein artemis
- EC
- 3.1.-.-
- Experimental structures
- 25
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 34 · 9 records with a druggable one
Structures
26 records of Q96SD1 in the MolNFT archive: 25 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3W1B | Crystal Structure of Human DNA ligase IV-Artemis Complex (Mercury Derivative) | x-ray diffraction | B | — | — |
| 3W1B | Crystal structure of human DNA ligase IV-artemis complex (mercury derivative) | x-ray diffraction | B | — | — |
| 3W1G | Crystal Structure of Human DNA ligase IV-Artemis Complex (Native) | x-ray diffraction | B | — | — |
| 3W1G | Crystal structure of human DNA ligase IV-artemis complex (native) | x-ray diffraction | B | — | — |
| 4HTP | Crystal structure of the DBD domain of human DNA ligase IV bound to Artemis peptide | x-ray diffraction | C, E | — | — |
| 4HTP | Crystal structure of the dbd domain of human DNA ligase IV bound to artemis peptide | x-ray diffraction | C, E | — | — |
| 6TT5 | Crystal structure of DCLRE1C/Artemis | x-ray diffraction | AAA | ZN, NI | 4 (best 0.53) |
| 6WNL | human Artemis/SNM1C catalytic domain, crystal form 2 | x-ray diffraction | A, B | ZN | 7 (best 0.79) |
| 6WNL | Human ARTEMIS/SNM1C catalytic domain, crystal form 2 | x-ray diffraction | A, B | ZN | — |
| 6WO0 | human Artemis/SNM1C catalytic domain, crystal form 1 | x-ray diffraction | A | ZN | 3 (best 0.60) |
| 6WO0 | Human ARTEMIS/SNM1C catalytic domain, crystal form 1 | x-ray diffraction | A | ZN | — |
| 7ABS | Structure of human DCLRE1C/Artemis in complex with DNA - re-evaluation of 6WO0 | x-ray diffraction | A | ZN | 5 (best 0.63) |
| 7ABS | Structure of human DCLRE1C/ARTEMIS in complex with DNA - re-evaluation of 6WO0 | x-ray diffraction | A | ZN | — |
| 7AF1 | The structure of Artemis/SNM1C/DCLRE1C with 2 Zinc ions | x-ray diffraction | A | ZN | 3 (best 0.58) |
| 7AF1 | The structure of ARTEMIS/SNM1C/DCLRE1C with 2 zinc ions | x-ray diffraction | A | ZN | — |
| 7AFS | The structure of Artemis variant D37A | x-ray diffraction | A | NI, ZN | 2 (best 0.58) |
| 7AFS | The structure of artemis variant D37A | x-ray diffraction | A | NI, ZN | — |
| 7AFU | The structure of Artemis variant H33A | x-ray diffraction | A | ZN | 5 (best 0.66) |
| 7AFU | The structure of artemis variant H33A | x-ray diffraction | A | ZN | — |
| 7AGI | The structure of Artemis variant H35D | x-ray diffraction | A | ZN | 4 (best 0.68) |
| 7AGI | The structure of artemis variant H35D | x-ray diffraction | A | ZN | — |
| 7APV | Structure of ARTEMIS/DCLRE1C/SNM1C in complex with ceftriaxone | x-ray diffraction | A | 9F2, ZN, NI | — |
| 7SGL | DNA-pk complex of DNA end processing | electron microscopy | D | MG, ZN | — |
| 7TYR | Cryo-EM structure of the basal state of the Artemis:DNA-PKcs complex (see COMPND 13/14) | electron microscopy | C | — | 1 (best 0.67) |
| 7TYR | Cryo-EM structure of the basal state of the ARTEMIS:DNA-pkcs complex (see compnd 13/14) | electron microscopy | C | — | — |
| Q96SD1 | AlphaFold monomer V2.0 prediction for protein artemis (Q96SD1) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7APV chain A against the predicted model Q96SD1: TM-score 1.00, RMSD 0.39 Å
- 7AF1 chain A against the predicted model Q96SD1: TM-score 1.00, RMSD 0.42 Å
- 7AF1 chain A against the predicted model Q96SD1: TM-score 1.00, RMSD 0.42 Å
- 7AFS chain A against the predicted model Q96SD1: TM-score 1.00, RMSD 0.43 Å
- 7AFS chain A against the predicted model Q96SD1: TM-score 1.00, RMSD 0.43 Å
- 6TT5 chain AAA against the predicted model Q96SD1: TM-score 1.00, RMSD 0.43 Å
- 6WO0 chain A against the predicted model Q96SD1: TM-score 0.99, RMSD 0.61 Å
- 6WO0 chain A against the predicted model Q96SD1: TM-score 0.99, RMSD 0.61 Å
- 7ABS chain A against the predicted model Q96SD1: TM-score 0.99, RMSD 0.62 Å
- 7ABS chain A against the predicted model Q96SD1: TM-score 0.99, RMSD 0.62 Å
Elsewhere
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