MolNFT v1 · #168668 · protein
Human ARTEMIS/SNM1C catalytic domain, crystal form 2
6WNL · Protein artemis: “Human ARTEMIS/SNM1C catalytic domain, crystal form 2”. X-ray diffraction, 1 ligand (ZN), 7 pockets (best druggability 0.79). MolNFT v1 #168668 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6WNL
- Type
- protein
- Length
- 712 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein artemis
- EC
- 3.1.-.-
- UniProt
- Q96SD1
- Ligands
- ZN
- Pockets
- 7 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 29% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Protein artemis (EC 3.1.-.-) | protein | 356 | 29% helix, 23% strand | Q96SD1 |
Ligands and binding sites
- ZN · Zinc ion · metal · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 843 | 0.79 | 0.82 | 84 | empty |
| 2 | 262 | 0.63 | 0.81 | 37 | empty |
| 3 | 202 | 0.61 | 0.82 | 26 | empty |
| 4 | 210 | 0.56 | 0.78 | 29 | empty |
| 5 | 212 | 0.52 | 0.77 | 33 | empty |
Interfaces
1 interface between chains.
- A–B · 950 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96SD1
- Elsewhere: RCSB PDB 6WNL · PDBe 6WNL · UniProt Q96SD1
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