UniProt Q96AY2
Crossover junction endonuclease EME1 (Q96AY2)
Crossover junction endonuclease EME1 (UniProt Q96AY2), EC 3.1.22.-: 20 experimental structures and 1 predicted model on GenesisL1, 31 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q96AY2
- Protein
- Crossover junction endonuclease EME1
- EC
- 3.1.22.-
- Experimental structures
- 20
- Predicted models
- 1
- Pockets
- 31 · 4 records with a druggable one
Structures
21 records of Q96AY2 in the MolNFT archive: 20 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2ZIU | Crystal structure of the Mus81-Eme1 complex | x-ray diffraction | B | — | — |
| 2ZIU | Crystal structure of the MUS81-EME1 complex | x-ray diffraction | B | — | — |
| 2ZIV | Crystal structure of the Mus81-Eme1 complex | x-ray diffraction | B | — | — |
| 2ZIV | Crystal structure of the MUS81-EME1 complex | x-ray diffraction | B | — | — |
| 2ZIW | Crystal structure of the Mus81-Eme1 complex | x-ray diffraction | B | — | — |
| 2ZIW | Crystal structure of the MUS81-EME1 complex | x-ray diffraction | B | — | — |
| 2ZIX | Crystal structure of the Mus81-Eme1 complex | x-ray diffraction | B | — | — |
| 2ZIX | Crystal structure of the MUS81-EME1 complex | x-ray diffraction | B | — | — |
| 4P0P | Crystal structure of Human Mus81-Eme1 in complex with 5'-flap DNA, and Mg2+ | x-ray diffraction | B | — | — |
| 4P0P | Crystal structure of human MUS81-EME1 in complex with 5'-flap DNA, and MG2+ | x-ray diffraction | B | — | — |
| 4P0Q | Crystal structure of Human Mus81-Eme1 in complex with 5'-flap DNA | x-ray diffraction | B | — | — |
| 4P0Q | Crystal structure of human MUS81-EME1 in complex with 5'-flap DNA | x-ray diffraction | B | — | — |
| 4P0R | human Mus81-Eme1-3'flap DNA complex | x-ray diffraction | B, D | — | — |
| 4P0R | Human MUS81-EME1-3'FLAP DNA complex | x-ray diffraction | B, D | — | — |
| 4P0S | human Mus81-Eme1-3'flap DNA complex | x-ray diffraction | B, D, F, H | — | — |
| 4P0S | Human MUS81-EME1-3'FLAP DNA complex | x-ray diffraction | B, D, F, H | — | — |
| 9F9A | Crystal structure of MUS81-EME1 bound by compound 12. | x-ray diffraction | B, D, F, H | — | 10 (best 0.77) |
| 9F9K | Crystal structure of MUS81-EME1 bound by compound 15. | x-ray diffraction | B, D | — | 6 (best 0.60) |
| 9F9L | Crystal structure of MUS81-EME1 bound by compound 16. | x-ray diffraction | B, D | — | 10 (best 0.61) |
| 9F9M | Crystal structure of MUS81-EME1 bound by compound 21. | x-ray diffraction | B, D | — | 5 (best 0.61) |
| Q96AY2 | AlphaFold monomer V2.0 prediction for crossover junction endonuclease EME1 (Q96AY2) | predicted | A | — | — |
Experiment against prediction
- 9F9M chain D against the predicted model Q96AY2: TM-score 0.99, RMSD 0.48 Å
- 9F9M chain B against the predicted model Q96AY2: TM-score 0.99, RMSD 0.50 Å
- 9F9K chain B against the predicted model Q96AY2: TM-score 0.99, RMSD 0.51 Å
- 9F9A chain B against the predicted model Q96AY2: TM-score 0.99, RMSD 0.50 Å
- 9F9L chain B against the predicted model Q96AY2: TM-score 0.99, RMSD 0.54 Å
- 9F9L chain D against the predicted model Q96AY2: TM-score 0.99, RMSD 0.59 Å
- 9F9K chain D against the predicted model Q96AY2: TM-score 0.99, RMSD 0.56 Å
- 9F9A chain D against the predicted model Q96AY2: TM-score 0.98, RMSD 0.63 Å
- 9F9A chain F against the predicted model Q96AY2: TM-score 0.98, RMSD 0.66 Å
- 9F9A chain H against the predicted model Q96AY2: TM-score 0.98, RMSD 0.70 Å
Elsewhere
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