UniProt Q90922
Netrin-1 (Q90922)
Netrin-1 (UniProt Q90922): 9 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q90922
- Protein
- Netrin-1
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 14 · 2 records with a druggable one
Structures
10 records of Q90922 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4PLM | Crystal Structure of Chicken Netrin-1 (LN-LE3) | x-ray diffraction | A | — | — |
| 4PLM | Crystal structure of chicken netrin-1 (ln-LE3) | x-ray diffraction | A | — | — |
| 4PLN | Crystal Structure of Chicken Netrin-1 (LN-LE3) complexed with mouse Neogenin (FN4-5) | x-ray diffraction | A, B | — | — |
| 4PLN | Crystal structure of chicken netrin-1 (ln-LE3) complexed with mouse neogenin (FN4-5) | x-ray diffraction | A, B | — | — |
| 4PLO | Crystal Structure of chicken Netrin-1 (LN-LE3) in complex with mouse DCC (FN4-5) | x-ray diffraction | A | — | — |
| 4PLO | Crystal structure of chicken netrin-1 (ln-LE3) in complex with mouse dcc (FN4-5) | x-ray diffraction | A | — | — |
| 7LER | Netrin-1 filament assembly | x-ray diffraction | A, B, C, E, D, F, G, H | NAG | — |
| 7LRF | Netrin-1 in complex with SOS | x-ray diffraction | A, B | NAG, GU4, YYJ, CA, NA, CL | 9 (best 0.54) |
| 7LRF | Netrin-1 in complex with sos | x-ray diffraction | A, B | NAG, GU4, YYJ, CA, NA, CL | — |
| Q90922 | AlphaFold monomer V2.0 prediction for netrin-1 (Q90922) | predicted | A | — | 5 (best 0.51) |
Ligands
Experiment against prediction
- 4PLN chain A against the predicted model Q90922: TM-score 0.98, RMSD 1.37 Å
- 4PLN chain A against the predicted model Q90922: TM-score 0.98, RMSD 1.37 Å
- 4PLO chain A against the predicted model Q90922: TM-score 0.97, RMSD 1.28 Å
- 4PLO chain A against the predicted model Q90922: TM-score 0.97, RMSD 1.28 Å
- 7LRF chain A against the predicted model Q90922: TM-score 0.97, RMSD 1.49 Å
- 7LRF chain A against the predicted model Q90922: TM-score 0.97, RMSD 1.49 Å
- 7LRF chain B against the predicted model Q90922: TM-score 0.97, RMSD 1.38 Å
- 7LRF chain B against the predicted model Q90922: TM-score 0.97, RMSD 1.38 Å
- 4PLM chain A against the predicted model Q90922: TM-score 0.96, RMSD 1.47 Å
- 4PLM chain A against the predicted model Q90922: TM-score 0.96, RMSD 1.47 Å
Elsewhere
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