UniProt Q8ZC05
Xanthine phosphoribosyltransferase (Q8ZC05)
Xanthine phosphoribosyltransferase (UniProt Q8ZC05), EC 2.4.2.22: 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q8ZC05
- Protein
- Xanthine phosphoribosyltransferase
- EC
- 2.4.2.22
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 5 · 3 records with a druggable one
Structures
7 records of Q8ZC05 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5XTK | Crystal structure of Xanthine-guanine phosphoribosyltransferase from Yersinia pestis | x-ray diffraction | A, B | SO4, 5GP | 2 (best 0.60) |
| 5XTK | Crystal structure of xanthine-guanine phosphoribosyltransferase from yersinia pestis | x-ray diffraction | A, B | SO4, 5GP | — |
| 6KP5 | crystal structure of Xanthine-guanine phosphoribosyltransferase (XGPRT) from Yersinia pestis in… | x-ray diffraction | A, B | SO4 | 2 (best 0.54) |
| 6KP5 | Crystal structure of xanthine-guanine phosphoribosyltransferase (xgprt) from yersinia pestis in… | x-ray diffraction | A, B | SO4 | — |
| 6KQC | Crystal structure of E136F mutant of Xanthine-guanine phosphoribosyltransferase from Yersinia pestis | x-ray diffraction | A, B | CL | — |
| 6KQC | Crystal structure of E136F mutant of xanthine-guanine phosphoribosyltransferase from yersinia pestis | x-ray diffraction | A, B | CL | — |
| Q8ZC05 | AlphaFold monomer V2.0 prediction for xanthine-guanine phosphoribosyltransferase (Q8ZC05) | predicted | A | — | 1 (best 0.55) |
Ligands
Experiment against prediction
- 6KP5 chain A against the predicted model Q8ZC05: TM-score 0.98, RMSD 0.61 Å
- 6KP5 chain A against the predicted model Q8ZC05: TM-score 0.98, RMSD 0.61 Å
- 5XTK chain B against the predicted model Q8ZC05: TM-score 0.97, RMSD 0.91 Å
- 5XTK chain A against the predicted model Q8ZC05: TM-score 0.97, RMSD 0.96 Å
- 5XTK chain A against the predicted model Q8ZC05: TM-score 0.97, RMSD 0.96 Å
- 6KQC chain A against the predicted model Q8ZC05: TM-score 0.97, RMSD 0.93 Å
- 6KQC chain A against the predicted model Q8ZC05: TM-score 0.97, RMSD 0.93 Å
- 6KP5 chain B against the predicted model Q8ZC05: TM-score 0.96, RMSD 1.17 Å
- 6KP5 chain B against the predicted model Q8ZC05: TM-score 0.96, RMSD 1.17 Å
- 6KQC chain B against the predicted model Q8ZC05: TM-score 0.95, RMSD 1.27 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.